Results 11 to 20 of about 526,776 (304)
Population-Wide Emergence of Antiviral Resistance during Pandemic Influenza [PDF]
, 2008 Background: The emergence of neuraminidase inhibitor resistance has raised concerns about the prudent use of antiviral drugs in response to the next influenza pandemic.
Wu, Jianhong +13 more
core +2 more sources
Epidemiological consequences of household-based antiviral prophylaxis for pandemic influenza [PDF]
, 2013 Antiviral treatment offers a fast acting alternative to vaccination; as such it is viewed as a first-line of defence against pandemic influenza in protecting families and households once infection has been detected.
M. J. Keeling +15 more
core +1 more source
Antiviral potential of cathelicidins [PDF]
, 2014 The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow.
Davidson, Donald J +4 more
core +1 more source
Emerging Microbes and Infections, 2021 African swine fever virus (ASFV) is the causal agent of a fatal disease of domestic swine for which no effective antiviral drugs are available. Recently, it has been shown that microtubule-targeting agents hamper the infection cycle of different viruses.
Samvel Sirakanyan +19 more
doaj +1 more source
Efficient and unbiased metagenomic recovery of RNA virus genomes from human plasma samples
Scientific Reports, 2017 RNA viruses cause significant human pathology and are responsible for the majority of emerging zoonoses. Mainstream diagnostic assays are challenged by their intrinsic diversity, leading to false negatives and incomplete characterisation.
Carmen F. Manso +2 more
doaj +1 more source
Scientific Reports, 2017 Management of infection with hepatitis B virus (HBV) remains a global health problem. Persistence of stable covalently closed circular DNA (cccDNA) during HBV replication is responsible for modest curative efficacy of currently licensed drugs. Novel gene
Tristan Scott +7 more
doaj +1 more source
Advances in designing Adeno-associated viral vectors for development of anti-HBV gene therapeutics
Virology Journal, 2021 Despite the five decades having passed since discovery of the hepatitis B virus (HBV), together with development of an effective anti-HBV vaccine, infection with the virus remains a serious public health problem and results in nearly 900,000 annual ...
Njabulo Mnyandu +3 more
doaj +1 more source
Microorganisms, 2023 Colibacillosis in chickens can cause the death of young stock, decrease weight gain and lead to significant economic losses. Currently, antibiotic therapy is the main method of treatment of infected animals, but unchecked use of antibiotics has led to ...
Pavel Alexyuk +5 more
doaj +1 more source
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]
, 2010 Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager +19 more
core +1 more source