Advances in designing Adeno-associated viral vectors for development of anti-HBV gene therapeutics
Despite the five decades having passed since discovery of the hepatitis B virus (HBV), together with development of an effective anti-HBV vaccine, infection with the virus remains a serious public health problem and results in nearly 900,000 annual ...
Njabulo Mnyandu +3 more
doaj +1 more source
Colibacillosis in chickens can cause the death of young stock, decrease weight gain and lead to significant economic losses. Currently, antibiotic therapy is the main method of treatment of infected animals, but unchecked use of antibiotics has led to ...
Pavel Alexyuk +5 more
doaj +1 more source
Antiviral strategies to control calicivirus infections [PDF]
Caliciviridae are human or non-human pathogenic viruses with a high diversity. Some members of the Caliciviridae, i.e. human pathogenic norovirus or rabbit hemorrhagic disease virus (RHDV), are worldwide emerging pathogens.
Mattevi, Andrea +8 more
core +1 more source
Optimization of a Sustainable Keratin Extraction Process from Waste Slaughterhouse Feathers: A Practice and Business Model Innovation [PDF]
The extraction of keratin from natural feathers has been studied for its use in various cosmetics and drug delivery applications. There are various reducing agents to dissolve the hard keratin such as sodium dodecyl sulfate and 2-mercaptoethanol, in the ...
Bechr Hamrita +7 more
doaj +1 more source
After a discussion of the principles of antiviral chemotherapy, treatment and chemoprophylaxis of the following virus infections are reviewed in detail: the various manifestations of herpes simplex virus infections, varicella-zoster, cytomegalovirus infections, Epstein-Barr virus infections, laryngeal papillomas, and influenza A.
openaire +3 more sources
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]
Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager +19 more
core +1 more source
Parainfluenza virus 5 genomes are located in viral cytoplasmic bodies whilst the virus dismantles the interferon-induced antiviral state of cells [PDF]
This work was supported by the Wellcome Trust.Although the replication cycle of parainfluenza virus type 5 (PIV5) is initially severely impaired in cells in an interferon (IFN)-induced antiviral state, the virus still targets STAT1 for degradation.
Carlos, T S +4 more
core +1 more source
Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro [PDF]
BACKGROUND: By modulating the antiviral immune response via vitamin D receptor, the active form of vitamin D (1,25-dihydroxyvitamin D, calcitriol) could play a central role in protection against respiratory virus infections.
Laza-Stanca, V +6 more
core +2 more sources
Potent effective antiviral drugs recently have been licensed for several viral diseases, ushering in a new era in the treatment of viral diseases. Several unique features in the process of a viral infection have been identified as target points for inhibition. The unique steps and the interfering compounds are the subject of this review.
Reines, Eric D., Gross, Peter A.
openaire +2 more sources
Clinical severe acute respiratory syndrome coronavirus 2 isolation and antiviral testing. [PDF]
Severe acute respiratory syndrome coronavirus 2 is an RNA virus currently causing a pandemic. Due to errors during replication, mutations can occur and result in cell adaptation by the virus or in the rise of new variants.
Mathez, G., Cagno, V.
core +1 more source

