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Broad-spectrum antiviral activity of ebselen [PDF]
Scientific ReportsBroad-spectrum antivirals are essential for pandemic preparedness, helping reduce mortality and mitigate social disruption. Ebselen, a synthetic organoselenium compound, is under investigation for treating various conditions, including viral infections ...
Kunlakanya Jitobaom +4 more
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Reactive oxygen species promotion drives auranofin’s antiviral activity against hepatitis E virus [PDF]
Journal of VirologyHepatitis E virus (HEV) causes roughly 20 million yearly global infections and is associated with chronic hepatitis, neurological sequelae, and pregnancy-related adverse outcomes that require antiviral intervention.
Kateland Tiller +5 more
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Antiviral Drug Research Proposal Activity
Journal of Microbiology & Biology Education, 2011 The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease.
Lisa Injaian +4 more
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Phosphorylation of Shiftless by casein kinase 1 δ/ε is required for its antiviral activity [PDF]
Journal of VirologyShiftless (SHFL) is a host antiviral factor that inhibits the viral −1 programmed ribosomal frameshifting (−1PRF). How the antiviral activity of SHFL is regulated is not known. Here, we report that the phosphorylation of SHFL by the casein kinase 1 delta
Yongle Wang +3 more
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The Antiviral Activity of Polyphenols. [PDF]
Mol Nutr Food ResABSTRACTPolyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a wide range of employment, from food production to medical usages.
Burkard M +5 more
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PLoS ONE, 2023 Vitamin D has been shown to have antiviral activity in a number of different systems. However, few studies have investigated whether the antiviral activity is exerted through the vitamin D receptor (VDR).
Janejira Jaratsittisin +4 more
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Antiviral activity of berberine [PDF]
Archives of Virology, 2020 AbstractPlants are a rich source of new antiviral, pharmacologically active agents. The naturally occurring plant alkaloid berberine (BBR) is one of the phytochemicals with a broad range of biological activity, including anticancer, anti-inflammatory and antiviral activity.
Alicja Warowicka +2 more
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MxA: a broadly acting effector of interferon-induced human innate immunity
Visualized Cancer Medicine, 2022 The Human MxA protein belongs to the dynamin superfamily of large GTPases and plays a vital role in human immunity against a broad spectrum of viruses. Evasion from MxA restriction accounts for the zoonotic transmission of many pathogenic viruses.
Liao Shuang, Gao Song
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Antiviral activities of flavonoids
Biomedicine & Pharmacotherapy, 2021 Flavonoids are natural phytochemicals known for their antiviral activity. The flavonoids acts at different stages of viral infection, such as viral entrance, replication and translation of proteins. Viruses cause various diseases such as SARS, Hepatitis, AIDS, Flu, Herpes, etc.
Badshah, Syed Lal +5 more
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Antiviral Activity of Lysozyme [PDF]
Nature, 1959 THE biological significance of lysozyme is not yet fully established. Its properties suggest that it has a role in immunism against bacterial infections. Lysozyme also seems to show antiviral activity. Previous observations support this possibility.
R, FERRARI, C, CALLERIO, G, PODIO
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