Results 111 to 120 of about 10,107,380 (301)

Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents [PDF]

, 2014
Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes.
A Owsianka, A Sigal, Aleem Siddiqui, Arvind H. Patel, AS Lok, AW Tarr, B Bartolini, B Sainz Jr, C Hezode, C Lee, C Nathan, C Sarrazin, CL Brimacombe, CM Lange, CT Jones, D Masson, D Trono, EJ Gane, Eric Soulier, F Kuonen, F Poordad, F Poordad, Fei Xiao, François Habersetzer, G Koutsoudakis, H Kwon, H Yan, H Zhu, Heidi Barth, I Fofana, I Fofana, I Fofana, IA Abela, IM Jacobson, Isabel Fofana, J Grove, J Lupberger, J Witteveldt, J Zhong, Jens Bukh, JG McHutchison, JM Gottwein, JM Gottwein, JM Pawlotsky, JM Pawlotsky, JM Pawlotsky, JM Timpe, L Rong, L Zona, Laura Heydmann, LW Meredith, MB Zeisel, MB Zeisel, Michel Doffoël, Mirjam B. Zeisel, MN Zahid, MS Sulkowski, MT Catanese, N Shi, O Lenz, P Zhong, PM Trembling, Q Sattentau, S Haid, T Pietschmann, T Pietschmann, T Wakita, Thomas F. Baumert, TJ Liang, TK Scheel, V Soriano, VD Cataldo, ZY Keck   +72 more
core   +6 more sources

The Antiviral Activity of Trifluoromethylthiolane Derivatives

Chemistry Proceedings, 2022
The search for new antiviral agents is an important task today. The aim of this study was to elucidate the impact of trifluoromethylthiolane derivatives on herpetic and adenoviral infections.
Liubov Artiukh, Olga Povnitsa, Yuriy Shermolovich, Sergiy Siry, Svitlana Zahorodnia   +4 more
doaj   +1 more source

In vitro antiviral activity of twenty-seven medicinal plant extracts from Southwest Nigeria against three serotypes of echoviruses

Virology Journal, 2018
Echoviruses, a serotype of enteroviruses, infect millions of people globally and there is no specific drug treatment or vaccine available for its management.
O. Ogbole, T. E. Akinleye, Peter A Segun, T. Faleye, A. Adeniji   +4 more
semanticscholar   +1 more source

In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]

, 2007
International ...
Croubels, Siska, De Backer, Patrick, Garré, Barbara, Nauwynck, Hans, NEYTS, J, NUGENT, J, VAN DER MEULEN, K   +6 more
core   +3 more sources

The Natural Compound Homoharringtonine Presents Broad Antiviral Activity In Vitro and In Vivo

Viruses, 2018
To complement traditional antivirals, natural compounds that act via host targets and present high barriers to resistance are of increasing interest.
Hui-jun Dong, Zhao Wang, Wen Meng, Cui-Cui Li, Yanxin Hu, Lei Zhou, Xiao-Jia Wang   +6 more
semanticscholar   +1 more source

Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure–Activity Relationship, and X-ray Structural Studies

Journal of Medicinal Chemistry, 2021
Here, we report the synthesis, structure–activity relationship studies, enzyme inhibition, antiviral activity, and X-ray crystallographic studies of 5-chloropyridinyl indole carboxylate derivatives as a potent class of SARS-CoV-2 chymotrypsin-like ...
Arun K. Ghosh, Jakka Raghavaiah, D. Shahabi, M. Yadav, B. Anson, E. Lendy, S. Hattori, Nobuyo Higashi-Kuwata, H. Mitsuya, A. Mesecar   +9 more
semanticscholar   +1 more source

Antiviral activity of silymarin against chikungunya virus [PDF]

, 2015
Citation: Lani, R., Hassandarvish, P., Chiam, C. W., Moghaddam, E., Chu, J. J. H., Rausalu, K., . . . Zandi, K. (2015). Antiviral activity of silymarin against chikungunya virus. Scientific Reports, 5, 10.
Abu Bakar, S., Chiam, C. W., Chu, J. J. H., Hassandarvish, P., Higgs, Stephen, Lani, R., Merits, A., Moghaddam, E., Rausalu, K., Vanlandingham, Dana, Zandi, K.   +10 more
core   +1 more source

SERINC Proteins Potentiate Antiviral Type I IFN Induction and Proinflammatory Signaling Pathways

Proceedings, 2020
T cell SERINC proteins were recently identified as human immunodeficiency virus (HIV) restriction factors that diminish viral infectivity by incorporation into virions.
Cong Zeng, Abdul A. Waheed, Tianliang Li, Jingyou Yu, Yi-Min Zheng, Jacob Yount, Haitao Wen, Eric O. Freed, Shan-Lu Liu   +8 more
doaj   +1 more source

Viruses and the cellular RNA decay machinery. [PDF]

, 2010
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core   +1 more source

Antiviral Activity of 3-Methyleneoxindole [PDF]

Antimicrobial Agents and Chemotherapy, 1974
3-Methyleneoxindole (MO), an oxidation product of the plant auxin indole-3-acetic acid, can selectively inhibit the replication of herpes-, mengo-, polioviruses, and Sindbis virus. The antiviral action of MO, a sulfhydryl binding compound, is neutralized by 2-mercaptoethanol if the latter is added soon after exposure of infected cells to MO.
I. Gordon, I. Gordon, D. Stevenson, D. Stevenson, H. S. Moyed, H. S. Moyed, V. Tuli, V. Tuli   +7 more
openaire   +3 more sources