Antiviral Activity of Graphene–Silver Nanocomposites against Non-Enveloped and Enveloped Viruses
The discovery of novel antiviral materials is important because many infectious diseases are caused by viruses. Silver nanoparticles have demonstrated strong antiviral activity, and graphene is a potential antimicrobial material due to its large surface ...
Yi-Ning Chen+4 more
semanticscholar +1 more source
Single-domain antibodies and their formatting to combat viral infections [PDF]
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies+4 more
core +2 more sources
The Antiviral Activity of Polyphenols
ABSTRACTPolyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a wide range of employment, from food production to medical usages.
Markus Burkard+5 more
openaire +2 more sources
Antiviral activity of cationic amphiphilic drugs
Introduction: Emerging and reemerging viral infections represent a major concern for human and veterinary public health and there is an urgent need for the development of broad-spectrum antivirals.
C. Salata+4 more
semanticscholar +1 more source
Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L.+8 more
core +2 more sources
Synthesis and antiviral activity of some novel indole-2-carboxylate derivatives
A series of novel indole-2-carboxylate derivatives were synthesized and assayed to determine their in vitro broad-spectrum antiviral activities. The biological results showed that some of the synthesized compounds exhibited potent broad-spectrum ...
Situ Xue+4 more
doaj +1 more source
Antiviral activity of animal venom peptides and related compounds
Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense.
Elida C G da Mata+3 more
semanticscholar +1 more source
The antiviral effect of a catalytic RNA-hydrolyzing antibody, 3D8 scFv, for intranasal administration against avian influenza virus (H1N1) was described.
Seungchan Cho+11 more
doaj +1 more source
Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes [PDF]
Encapsulation of oligonucleotides in antibody-targeted liposomes (immunoliposomes) which bind to target cells permits intracellular delivery of the oligonucleotides.
Akhtar+42 more
core +1 more source
Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes [PDF]
Although the relative contribution of different immune effector functions to clearing tissues of cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally been accepted as essential. In this report, we show that under certain
Jonjic, Stipan+4 more
core