Results 141 to 150 of about 250,897 (215)

YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice. [PDF]

Nat Commun
Nan J, Shuai H, Qiao J, Zeng R, Du L, Chen Y, Yoon C, Hu J, Guo W, Wang L, Huang C, Zhu L, Li Y, Zhang S, Deng X, Sun J, Du L, Ma R, Huang Q, Lei J, Chu H, Yang S.   +21 more
europepmc   +1 more source

Ecology and evolution of pyrazines in insects

Biological Reviews, EarlyView.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk, Niklas Wahlberg, Johanna Mappes   +2 more
wiley   +1 more source

Validation of Recombinant Type I Interferon Antiviral Activity Against Porcine Epidemic Diarrhea Virus In Vitro and In Vivo. [PDF]

Vet Sci
Du L, Zhang R, Wang S, Han S, Zhang S, Meng F, Fang Z, Wang X, Zhao R, Dai R, Qin L, Lyu C, Wang G.   +12 more
europepmc   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Identification of Marine-Derived Compounds with Potent Antiviral Activity in a Recombinant HBV cccDNA Cell Model. [PDF]

ACS Omega
Song X, Ji Y, Cong M, Yang D, Wang MW, Wang J, Zhou Q, Chen J.   +7 more
europepmc   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

A hedgehog cathelicidin-derived peptide exhibits antiviral activity against herpes simplex virus type 1 infection. [PDF]

Front Microbiol
Deng E, Pei Y, Yuan K, Yang J, Cao SA, Yang X, Li G, Liang L, Jin L, Zhu T.   +9 more
europepmc   +1 more source

Synthesis and Functional Properties of Fluorinated Phosphonate‐Substituted Porphyrins: Excellent Photosensitizers and Robust Precursors for Photoactive Langmuir–Schaefer Films

Chemistry – A European Journal, EarlyView.
This is a comprehensive study of new family of high functionalized meso‐tetraarylporphyrins. A synthetic approach to phosphonate‐substituted fluorinated porphyrins was developed. These compounds were investigated with respect to singlet oxygen generation and photostability.
Azhar Kechiche, Cyrille Monnereau, Chantal Andraud, Alla Bessmertnykh‐Lemeune, Yoann Rousselin, Andrey V. Cheprakov, Elizaveta V. Ermakova, Alexandra I. Zvyagina, Habib Nasri   +8 more
wiley   +1 more source

Discovery of a Marine <i>Beauveria bassiana</i> Polysaccharide with Antiviral Activity Against Tobacco Mosaic Virus. [PDF]

Mar Drugs
Qiu X, Jiao L, Xue J, Xu G, Tang X.
europepmc   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source