Results 11 to 20 of about 355,010 (330)

Antiviral Activity of Ribosome-Inactivating Proteins

Toxins, 2021
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2.2.22) that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs have been investigated for more than four decades.
Lucía Citores, Rosario Iglesias, José M. Ferreras   +2 more
doaj   +1 more source

Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships

Frontiers in Chemistry, 2022
Viruses spread rapidly and are well-adapted to changing environmental events. They can infect the human body readily and trigger fatal diseases. A limited number of drugs are available for specific viral diseases, which can lead to non-efficacy against ...
Yajing Guo, Anna Ma, Xinyan Wang, Chen Yang, Xi Chen, Gen Li, Feng Qiu, Feng Qiu   +7 more
doaj   +1 more source

Antiviral Activity of CD437 Against Mumps Virus

Frontiers in Microbiology, 2021
Many efforts have been dedicated to the discovery of antiviral drug candidates against the mumps virus (MuV); however, no specific drug has yet been approved.
Fumihiro Kato, Yuichiro Nakatsu, Keiko Murano, Aika Wakata, Toru Kubota, Takayuki Hishiki, Toshiyuki Yamaji, Minoru Kidokoro, Minoru Kidokoro, Hiroshi Katoh, Makoto Takeda   +10 more
doaj   +1 more source

Poly(ADP-ribose) potentiates ZAP antiviral activity.

PLoS Pathogens, 2022
Zinc-finger antiviral protein (ZAP), also known as poly(ADP-ribose) polymerase 13 (PARP13), is an antiviral factor that selectively targets viral RNA for degradation.
Guangai Xue, Klaudia Braczyk, Daniel Gonçalves-Carneiro, Daria M Dawidziak, Katarzyna Sanchez, Heley Ong, Yueping Wan, Kaneil K Zadrozny, Barbie K Ganser-Pornillos, Paul D Bieniasz, Owen Pornillos   +10 more
doaj   +1 more source

The Antiviral Activities of ISG15

Journal of Molecular Biology, 2013
Post-translational protein modification is an important strategy for the regulation of the cell proteome independent of the need for new gene expression. Ubiquitin and ubiquitin-like modifiers mediate the regulation of protein levels, signaling pathways, vesicular trafficking, and many other cellular processes through their covalent conjugation to ...
David J. Morales, Deborah J. Lenschow
openaire   +3 more sources

Antiviral Activities of Biflavonoids

Planta Medica, 1999
Biflavonoids such as amentoflavone (1), agathisflavone (2), robustaflavone (3), hinokiflavone (4), volkensiflavone (5), rhusflavanone (7), succedaneflavanone (9), all isolated from Rhus succedanea and Garcinia multiflora, as well as their methyl ethers and acetates, volkensiflavone hexamethyl ether (6), rhusflavanone hexaacetate (8), and ...
Lin, Y. M., Flavin, M. T., Schure, R., Chen, F. C., Sidwell, R., Barnard, Dale L., Huffman, J. H., Kern, E. R.   +7 more
openaire   +3 more sources

Polysaccharides as antiviral agents: antiviral activity of carrageenan [PDF]

Antimicrobial Agents and Chemotherapy, 1987
A number of polysaccharides showed good antiviral activity against several animal viruses. At 5 micrograms/ml, carrageenan prevented the cell monolayer from destruction by herpes simplex virus type 1 (HSV-1) growth. At 10 micrograms/ml, carrageenan reduced the formation of new infectious HSV-1 by almost five logs.
González, M. E., Alarcón, Balbino, Carrasco, Luís   +2 more
openaire   +3 more sources

Potential antiviral activity of metformin against human Adenovirus-7 [PDF]

Microbes and Infectious Diseases
Background: Human adenovirus 7(HAdV-7) cause acute respiratory tract infections with high morbidity and mortality rates in children and immunocompromised adults. Metformin is a natural oral antihyperglycemic drug, that possesses antiviral activity.
Ibrahim Abdelwahab, Gihan ELBatouti
doaj   +1 more source

Antiviral and virucidal activity of sodium deoxyribonucleate and its complex with iron against viruses of different kingdoms and families

Вопросы вирусологии, 2023
Introduction. The urgent problem of modern medicine is the fight against acute respiratory viral infections (ARVI). To combat ARVI, drugs of wide antiviral potency are needed, as well as immunomodulating drugs. Such antiviral and immunomodulatory effects
Dmitry N. Nosik, Lyudmila B. Kalnina, Olga A. Lobach, Marina S. Chataeva, Elena V. Berezhnaya, Marina S. Bochkova, Irina A. Kiseleva, Lyudmila M. Selimova, Nikolai N. Nosik   +8 more
doaj   +1 more source

Cyclopentenylcytosine (CPE-C): In Vitro and In Vivo Evaluation as an Antiviral against Adenoviral Ocular Infections

Molecules, 2023
Adenoviruses are the major cause of ocular viral infections worldwide. Currently, there is no approved antiviral treatment for these eye infections. Cyclopentenylcytosine (CPE-C) is an antiviral that has demonstrated activity against more than 20 viruses.
Eric G. Romanowski, Kathleen A. Yates, Y. Jerold Gordon   +2 more
doaj   +1 more source