Results 21 to 30 of about 355,010 (330)

MECHANISMS OF ANTIVIRAL ACTIVITY OF FLAVONOIDS [PDF]

Biotechnologia Acta, 2023
The article examines the multifaceted mechanisms underlying the antiviral activity of flavonoids, compounds widely distributed in the plant kingdom. The aim of the work was to review literature data on mechanisms of antiviral activity of flavonoids.
Golembiovska O.I. , Bespalova O.Ya., Prosvetova A.B., Samsonenko S.M. , Poyedynok N.L.   +4 more
doaj   +1 more source

Evaluation of Essential Oils and Extracts of Rose Geranium and Rose Petals as Natural Preservatives in Terms of Toxicity, Antimicrobial, and Antiviral Activity

Pathogens, 2021
Essential oils (EOs) and extracts of rose geranium (Pelargonium graveolens) and petals of rose (Rosa damascena) have been fully characterized in terms of composition, safety, antimicrobial, and antiviral properties. They were analyzed against Escherichia
Chrysa Androutsopoulou, Spyridoula D. Christopoulou, Panagiotis Hahalis, Chrysoula Kotsalou, Fotini N. Lamari, Apostolos Vantarakis   +5 more
doaj   +1 more source

Antiviral Activities of Silymarin and Derivatives [PDF]

Molecules, 2019
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. Recent studies have also documented the antiviral activities of silymarin and its derivatives against several viruses, including the flaviviruses (hepatitis C virus and dengue virus), togaviruses (Chikungunya virus and
Hsin Ya Hsu, Alagie Jassey, Liang Tzung Lin, Ching Hsuan Liu   +3 more
openaire   +4 more sources

First Principle Simulation of Coated Hydroxychloroquine on Ag, Au and Pt Nanoparticle as a Potential Candidate for Treatment of SARS-CoV-2 (COVID-19) [PDF]

, 2020
The {\it{in vitro}} antiviral activity of Hydroxychloroquine (HCQ) and chloroquine (CQ) against SARS-CoV-2 from the first month of pandemic proposed these drugs as the appropriate therapeutic candidate, although their side effect directed the clinical test toward optimizing the safe utilization strategies.
arxiv   +1 more source

Assessment of in-vitro cytotoxicity and in-ovo virucidal antiviral efficacy of various plant extracts and bioactive molecules [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
The viral diseases that occurred in recent years have increased the interest in non-toxic to healthy cells and naturally isolated agents to struggle with these diseases.
Furkan Ozan ÇÖVEN, Seray GÜR, Ece UYAR, Karrar Ali Mohammed Hasan ALSAKINI, Fatih KARABEY, Fethiye ÇÖVEN, İhsan ÇALIŞ, Ayşe NALBANTSOY   +7 more
doaj   +1 more source

The antiviral activities of TRIM proteins

Current Opinion in Microbiology, 2021
Tripartite motif (TRIM) proteins are a highly versatile family of host-cell factors that play an integral role in the mammalian defense against pathogens. TRIM proteins regulate either transcription-dependent antiviral responses such as pro-inflammatory cytokine induction, or they modulate other important cell-intrinsic defense pathways like autophagy.
Konstantin M. J. Sparrer, Michaela U. Gack, Michaela U. Gack, Lennart Koepke   +3 more
openaire   +4 more sources

VDDB: a comprehensive resource and machine learning platform for antiviral drug discovery [PDF]

arXiv, 2022
Virus infection is one of the major diseases that seriously threaten human health. To meet the growing demand for mining and sharing data resources related to antiviral drugs and to accelerate the design and discovery of new antiviral drugs, we presented an open-access antiviral drug resource and machine learning platform (VDDB), which, to the best of ...
arxiv  

Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2

Frontiers in Pharmacology, 2022
This study presents the very first report on the in vitro antiviral activity of selected essential oils of Lamiaceae plant species and their monoterpenes against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Sanja Ćavar Zeljković, Sanja Ćavar Zeljković, Ermin Schadich, Petr Džubák, Petr Džubák, Marián Hajdúch, Marián Hajdúch, Petr Tarkowski, Petr Tarkowski   +8 more
doaj   +1 more source

Antiviral activities of whey proteins [PDF]

Applied Microbiology and Biotechnology, 2015
Milk contains an array of proteins with useful bioactivities. Many milk proteins encompassing native or chemically modified casein, lactoferrin, alpha-lactalbumin, and beta-lactoglobulin demonstrated antiviral activities. Casein and alpha-lactalbumin gained anti-HIV activity after modification with 3-hydroxyphthalic anhydride.
Randy Chi Fai Cheung, Denis Tsz-Ming Ip, John Wong, Jiang Xia, Tzi Bun Ng, Yan Wang, David Chi Cheong Wan   +6 more
openaire   +3 more sources

Three-fold mechanism of inhibition of SARS-CoV-2 infection by the interaction of the spike glycoprotein with heparin [PDF]

arXiv, 2021
Heparin has been found to have antiviral activity against SARS-CoV-2. Here, by means of sliding window docking, molecular dynamics simulations and biochemical assays, we investigate the binding mode of heparin to the virus spike glycoprotein and the molecular basis for its antiviral activity.
arxiv