Results 31 to 40 of about 10,107,380 (301)

A review of the antiviral activity of Chitosan, including patented applications and its potential use against COVID‐19

Journal of Applied Microbiology, 2021
Chitosan is an abundant organic polysaccharide, which can be relatively easily obtained by chemical modification of animal or fungal source materials. Chitosan and its derivatives have been shown to exhibit direct antiviral activity, to be useful vaccine
N. Jaber, M. Al-Remawi, Faisal Al-Akayleh, N. Al-Muhtaseb, I. Al-Adham, P. Collier   +5 more
semanticscholar   +1 more source

Antioxidant Capacity and Antimicrobial Activity of Commercial Samples of Guava Leaves (\u3cem\u3ePsidium guajava\u3c/em\u3e) [PDF]

, 2020
Psidium guajava is a small tree native to South and Central America. Guava leaves have traditionally been used for treating different illnesses. These benefits can be attributed to phenolics and flavonoids produced by guava.
Alsaidi, Sahar, Bonnaire, Thierry, Cornejal, Nadjet, Cruz Rodriguez, Gearoff, Cruz, Victor, Fernandez Romero, Jose, Gomez Ramirez, Aned, Koroch, Adolfina, Melo, Claudia, Priano, Christine, Sorel, Victor, Zydowsky, Thomas M   +11 more
core   +2 more sources

A Review of Medicinal Plants with Antiviral Activity Available in Bangladesh and Mechanistic Insight Into Their Bioactive Metabolites on SARS-CoV-2, HIV and HBV

Frontiers in Pharmacology, 2021
Currently, viral infection is the most serious health issue which causing unexpected higher rate of death globally. Many viruses are not yet curable, such as corona virus-2 (SARS-CoV-2), human immunodeficiency virus (HIV), hepatitis virus, human ...
S. C. Bachar, K. Mazumder, R. Bachar, Asma Aktar, Mamun Al Mahtab   +4 more
semanticscholar   +1 more source

Anti–SARS‐CoV‐2 Repurposing Drug Database: Clinical Pharmacology Considerations

CPT: Pharmacometrics & Systems Pharmacology, 2021
A critical step to evaluate the potential in vivo antiviral activity of a drug is to connect the in vivo exposure to its in vitro antiviral activity. The Anti–SARS‐CoV‐2 Repurposing Drug Database is a database that includes both in vitro anti–SARS‐CoV‐2 ...
Xinyuan Zhang, Yuching Yang, Manuela Grimstein, Guansheng Liu, Eliford Kitabi, Jianghong Fan, Ying‐Hong Wang, Justin Earp, James L. Weaver, Hao Zhu, Jiang Liu, Kellie S. Reynolds, Shiew‐Mei Huang, Yaning Wang   +13 more
doaj   +1 more source

Antiviral Activity of Ribosome-Inactivating Proteins

Toxins, 2021
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2.2.22) that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs have been investigated for more than four decades.
Lucía Citores, Rosario Iglesias, José M. Ferreras   +2 more
doaj   +1 more source

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance The previous lack of consensus around the use of hydroxychloroquine for COVID-19 patients underlines the need to thoroughly assess the in vivo efficacy of drugs against SARS-CoV-2.
Suzanne J. F. Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan ter Horst, L. Liesenborghs, Bart Hens, V. Vergote, E. Heylen, Karine Barthelemy, E. Maas, Carolien de Keyzer, Lindsey Bervoets, Jasper Rymenants, Tina Van Buyten, Xin Zhang, R. Abdelnabi, J. Pang, Rachel J. Williams, H. Thibaut, K. Dallmeier, R. Boudewijns, Jens Wouters, P. Augustijns, N. Verougstraete, C. Cawthorne, J. Breuer, C. Solas, B. Weynand, P. Annaert, I. Spriet, G. Vande Velde, J. Neyts, J. Rocha-Pereira, Leen Delang   +34 more
semanticscholar   +1 more source

Antiviral Activity of Carrageenans and Processing Implications

Marine Drugs, 2021
Carrageenan and carrageenan oligosaccharides are red seaweed sulfated carbohydrates with well-known antiviral properties, mainly through the blocking of the viral attachment stage. They also exhibit other interesting biological properties and can be used
Milena Álvarez-Viñas, S. Souto, N. Flórez-Fernández, M. Torres, I. Bandín, H. Domínguez   +5 more
semanticscholar   +1 more source

Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships

Frontiers in Chemistry, 2022
Viruses spread rapidly and are well-adapted to changing environmental events. They can infect the human body readily and trigger fatal diseases. A limited number of drugs are available for specific viral diseases, which can lead to non-efficacy against ...
Yajing Guo, Anna Ma, Xinyan Wang, Chen Yang, Xi Chen, Gen Li, Feng Qiu, Feng Qiu   +7 more
doaj   +1 more source

Grifonin-1: A Small HIV-1 Entry Inhibitor Derived from the Algal Lectin, Griffithsin [PDF]

, 2010
Background: Griffithsin, a 121-residue protein isolated from a red algal Griffithsia sp., binds high mannose N-linked glycans of virus surface glycoproteins with extremely high affinity, a property that allows it to prevent the entry of primary isolates
A Alexaki, A Makinson, AJ Miles, AL Cole, Alan J. Waring, Alexander M. Cole, AM Cole, Amy L. Cole, AV Efimov, B Giomarelli, B Hess, BR O'Keefe, C Nobile, CA Derdeyn, CC Liu, Cheryl A. Stoddart, Chun-Ling Jung, CM Haggerty, CT Wild, D Finzi, DD Richman, DM Byler, E Leikina, EJ Cohn, Ewa D. Micewicz, G Pantaleo, GB Fields, Hai Luong, HM Temin, HR Bokesch, HR Bokesch, I Botos, J Embretson, JJ Kiser, L Vandekerckhove, L Vandekerckhove, L Zeitlin, LT Rimsky, Martin L. Phillips, MD Bruch, MR Boyd, NE Ziolkowska, NE Ziolkowska, NE Ziolkowska, NE Ziolkowska, P Emau, P Lusso, Piotr Ruchala, Pratikhya Pratikhya, RI Lehrer, Shantanu Sharma, SM Owen, SN McCurdy, T Mori, T Mori, T Pierson, TM Laue, W Kabsch, W Wang, W Wang, WC Johnson, WC Johnson Jr, X Wei   +62 more
core   +8 more sources

Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity

bioRxiv, 2020
Antiviral therapy is urgently needed to combat the coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
M. Hoffmann, Heike Hofmann-Winkler, Joan C. Smith, Nadine Krüger, L. K. Sørensen, O. Søgaard, J. Hasselstrøm, M. Winkler, Tim Hempel, L. Raich, S. Olsson, Takashi Yamazoe, Katsura Yamatsuta, H. Mizuno, S. Ludwig, F. Noé, J. Sheltzer, Mads Kjolby, S. Pöhlmann   +18 more
semanticscholar   +1 more source