Results 31 to 40 of about 193,162 (335)
, 2009 Antiviral agents are drugs approved in the USA by the Food and Drug Administration (FDA) for the treatment or control of viral infections. Available antiviral agents mainly target stages in the viral life cycle. The target stages in the viral life cycle are; viral attachment to host cell, uncoating, synthesis of viral mRNA, translation of mRNA ...
Paintsil, E., Cheng, Yung-Chi
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Broad-spectrum antiviral agents [PDF]
Frontiers in Microbiology, 2015 Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular defense system.
Wen Meng +3 more
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Negligible risks of hepatocellular carcinoma during biomarker-defined immune-tolerant phase for patients with chronic hepatitis B [PDF]
Clinical and Molecular Hepatology, 2021 Background/Aims The immune-tolerant (IT) phase of chronic hepatitis B (CHB) patients is not generally indicative of antiviral therapy (AVT). We assessed and compared the risk of hepatocellular carcinoma (HCC) during the IT-phase stringently defined by a ...
Mi Young Jeon +8 more
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Progress with antiviral agents [PDF]
FEBS Letters, 1974 It is perhaps pretentious to employ the current popular term ‘antiviral chemotherapy’ when only three classes of compounds are officially approved for limited clinical application: N-methylisatin3i adamantamine, for prophylaxis in humans subject to influenza A-2 virus infections [2,3] ; and 5iodo-2’-deoxyuridine (IUdR) for therapy of herpes simplex ...
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Recent Research Progress: Discovery of Anti-Plant Virus Agents Based on Natural Scaffold
Frontiers in Chemistry, 2022 Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of the world and huge economic losses every year. Antiviral agents are one of the most effective ways to control plant virus diseases.
Jixiang Chen +6 more
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Wolbachia and arbovirus inhibition in mosquitoes [PDF]
, 2013 Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
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Antiviral Potential of Nanoparticles—Can Nanoparticles Fight Against Coronaviruses?
Nanomaterials, 2020 Infectious diseases account for more than 20% of global mortality and viruses are responsible for about one-third of these deaths. Highly infectious viral diseases such as severe acute respiratory (SARS), Middle East respiratory syndrome (MERS) and ...
Sangiliyandi Gurunathan +7 more
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Viruses, 2023 Enterovirus A71 (EV71), coxsackievirus A16 (CVA16), and coxsackievirus B3 (CVB3) are pathogenic members of the Picornaviridae family that cause a range of diseases, including severe central nervous system complications, myocarditis, and pancreatitis ...
Jae-Hyoung Song +10 more
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The evaluation of liver fibrosis regression in chronic hepatitis C patients after the treatment with direct-acting antiviral agents – A review of the literature [PDF]
, 2019 The second-generation of direct-acting antiviral agents are the current treatment for chronic viral hepatitis C infection. To evaluate the regression of liver fibrosis in patients receiving this therapy, liver biopsy remains the most accurate method, but
Alexescu, Teodora G +12 more
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Polysaccharides as antiviral agents: antiviral activity of carrageenan [PDF]
Antimicrobial Agents and Chemotherapy, 1987 A number of polysaccharides showed good antiviral activity against several animal viruses. At 5 micrograms/ml, carrageenan prevented the cell monolayer from destruction by herpes simplex virus type 1 (HSV-1) growth. At 10 micrograms/ml, carrageenan reduced the formation of new infectious HSV-1 by almost five logs.
González, M. E. +2 more
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