Results 101 to 110 of about 3,701,075 (393)

Predictability of IL-28B-polymorphism on protease-inhibitor-based triple-therapy in chronic HCV-genotype-1 patients: A meta-analysis

open access: yes, 2014
AIM: To investigate the predictability of interleukin-28B single nucleotide polymorphism rs12979860 with respect to sustained virological response (SVR) in chronically hepatitis C virus (HCV) genotype-1 patients treated with a protease-inhibitor and ...
Amanzada, Ahmad   +3 more
core   +1 more source

Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses

open access: yesMolecules, 2020
Respiratory RNA viruses are responsible for recurrent acute respiratory illnesses that still represent a major medical need. Previously we developed a large variety of benzimidazole derivatives able to inhibit these viruses.
Valeria Francesconi   +4 more
semanticscholar   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

open access: yesAdvanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger   +9 more
wiley   +1 more source

17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle [PDF]

open access: yes, 2016
Rationale & Aim: Estrogen and estrogen-mediated signalling protect from hepatitis C virus through incompletely understood mechanisms. We aimed to ascertain which phase(s) of HCV life cycle is/are affected by estrogens.
Barbaglia, Matteo N.   +10 more
core   +2 more sources

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

Tribbles pseudokinase 3 promotes enterovirus A71 infection via dual mechanisms

open access: yesEmerging Microbes and Infections
Enterovirus A71 (EV-A71) is the main pathogen causing hand, foot and mouth disease (HFMD) in children and occasionally associated with neurological diseases such as aseptic meningitis, brainstem encephalitis (BE) and acute flaccid paralysis.
Huiqiang Wang   +8 more
doaj   +1 more source

New antiviral agents and new treatments on the horizon for the management of viral hepatitis

open access: yesThalassemia Reports, 2011
Transfusion dependant patients are at risk of acquiring transfusiontransmitted viral infections including Hepatitis B virus (HBV) and Hepatitis C (HCV). These infections can lead to cirrhosis and hepatic cancer. Standard treatment, although with improved
M. Sönmezoğlu
doaj   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

MODERN CONCEPTS OF FARMACOTHERAPY OF HERPES ZOSTER [PDF]

open access: yesСаратовский научно-медицинский журнал, 2008
In the reviewofmodern concept ofpathology and pharmacotherapyofherpes zostervirus were analyzed. Complex therapy of varicella-zoster virus includes antiviral, immunobiological agents and drugs, affecting pathogenesis of the disease.
A.L. Bakulev   +2 more
doaj  

Carbazole Derivatives as Antiviral Agents: An Overview

open access: yesMolecules, 2019
Viruses represent the most common cause of infectious diseases worldwide and those with rapid propagation and high infection rates cause human and animal pandemics. These fast-spreading diseases are generally treated with antiviral drugs but, often, drug
Anna Caruso   +7 more
doaj   +1 more source

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