Results 171 to 180 of about 286,395 (314)

Biomedical Applications of Nanozymes: An Enzymology Perspective

Angewandte Chemie, EarlyView.
With a lens of enzymology, this review compares nanozymes with enzymes using the Michaelis‐Menten model and differences in KM and kcat along with catalysis in complex biological environment. The implications of these differences in biomedical applications of nanozymes are then described with a statistical analysis of the trend of therapeutic use of ...
Vasily G. Panferov, Xiaohan Zhang, Ka‐Ying Wong, Jung Heon Lee, Juewen Liu   +4 more
wiley   +2 more sources

Engineering Metal‐Organic‐Framework‐Based STING Nanoagonists for PROTAC‐Enhanced Cancer Chemo‐Metalloimmunotherapy

Advanced Science, EarlyView.
Schematic overview of PROTAC‐enhanced chemo‐metalloimmunotherapy, integrating senescence induction, multi‐modal STING pathway activation, PD‐L1 blockade, and immune amplification via coordinated PROTACs, metal ions, and chemotherapy to elicit robust antitumor immunity and circumvent immune evasion.
Zhenzhen Chen, Zhe Feng, Siyuan Wang, Jingjing Zhang   +3 more
wiley   +1 more source

Synthesis of L-2-deoxythreose nucleosides as potential antiviral agents [PDF]

, 2010
Toti, Kiran, Van Calenbergh, Serge
core   +3 more sources

Studies on antiviral agents. I. Synthesis and in vitro antiviral activity of new kanamycin A derivatives.

, 1985
Keiji Matsuda, Nobuyoshi Yasuda, Hideo Tsutsumi, TAKAO TAKAYA   +3 more
openalex   +2 more sources

Mechanistic Insights in Surface Engineering of Micro‐/Nanocomposite Phase Change Materials for Thermal Energy Storage: A Review

Advanced Energy and Sustainability Research, EarlyView.
This review examines surface‐engineered phase change material composites as vital solutions for escalating thermal energy storage demands driven by urbanization. It elucidates their enhanced performance through chemical mechanisms, diverse compositions, and preparation strategies, emphasizing the role of carbon‐based additives in improving thermal ...
Laxman Singh, Saravanakumar Balakrishnan, Joseph Johnson William, Sheikdawood Parveen, Ponnachiyur Aruchamy Periasamy, Rajeev Kumar, Anshuman Srivastava, Sunil Kumar, Amit Kumar Shringi, Dimple Kumari, Ambrish Singh, Fei Yan   +11 more
wiley   +1 more source

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source

Clinical applications of antiviral agents for chemophrophylaxis and therapy of respiratory viral infections

, 1985
Frederick G. Hayden
openalex   +1 more source

Selected Plant Triterpenoids and Their Derivatives as Antiviral Agents. [PDF]

Molecules, 2023
Wimmerová M, Bildziukevich U, Wimmer Z.
europepmc   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

Advanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee, Jaehong Min, Sujin Kim, Jihoon Ko   +3 more
wiley   +1 more source

Revisiting the monocrotaline‐treated rat as a model of inflammatory lung disease: COVID‐19 and future pandemic threats?

Animal Models and Experimental Medicine, EarlyView.
In this review, the pathological, molecular, and cellular changes observed in the COVID‐19 lung are compared to those in the laboratory rat treated with monocrotaline (MCT). Similarities that reflect common changes associated with inflammation and endothelial cell dysfunction are observed in both states, leading to a lung pathology characterized by ...
Luke P. Kris, Dani‐Louise Dixon, Shailesh Bihari, Jillian M. Carr   +3 more
wiley   +1 more source