Results 41 to 50 of about 3,623,509 (414)
Comparing antiviral strategies against COVID-19 via multiscale within-host modelling [PDF]
R. Soc. Open Sci., 8, 210082 (2021), 2020 Within-host models of COVID-19 infection dynamics enable the merits of different forms of antiviral therapy to be assessed in individual patients. A stochastic agent-based model of COVID-19 intracellular dynamics is introduced here, that incorporates essential steps of the viral life cycle targeted by treatment options. Integration of model predictions
arxiv +1 more source
International Journal of Molecular Sciences, 2020 Essential oils have shown promise as antiviral agents against several pathogenic viruses. In this work we hypothesized that essential oil components may interact with key protein targets of the 2019 severe acute respiratory syndrome coronavirus 2 (SARS ...
J. D. da Silva +3 more
semanticscholar +1 more source
Metal Complexes as Antiviral Agents for SARS‐CoV‐2
ChemBioChem, 2021 The severe acute respiratory syndrome – coronavirus 2 (SARS‐CoV‐2), the infectious agent responsible for COVID‐19 – has caused more than 2.5 million deaths worldwide and triggered a global pandemic. Even with successful vaccines being delivered, there is
J. Karges, Seth M. Cohen
semanticscholar +1 more source
Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral Drugs
Emerging Infectious Diseases, 2004 Severe acute respiratory syndrome (SARS) is an infectious disease caused by a newly identified human coronavirus (SARS-CoV). Currently, no effective drug exists to treat SARS-CoV infection.
Emily L.C. Tan +6 more
doaj +1 more source
Variability in antifungal and antiviral use in hospitalized children [PDF]
, 2017 We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S +6 more
core +2 more sources
Antiviral Agents – Benzazine Derivatives [PDF]
Chemistry of Heterocyclic Compounds, 2021 The review outlines the results of studies of the antiviral activity of quinoline, quinoxaline, and quinazoline derivatives published over the past 5 years. The supplied data indicate the enormous potential of benzazines for the design of effective antiviral drugs.
Emiliya V. Nosova +4 more
openaire +3 more sources
Comparison of Antiviral Agents for Seasonal Influenza Outcomes in Healthy Adults and Children
JAMA Network Open, 2021 Key Points Question What antiviral agents for treating seasonal influenza are associated with the most safety and best outcomes among healthy adults and children?
Jen-Wei Liu +4 more
semanticscholar +1 more source
Plant-derived lignans as potential antiviral agents: a systematic review
Phytochemistry Reviews, 2021 Medicinal plants are one of the most important sources of antiviral agents and lead compounds. Lignans are a large class of natural compounds comprising two phenyl propane units. Many of them have demonstrated biological activities, and some of them have
Xin-Ya Xu +4 more
semanticscholar +1 more source
mBio, 2022 Amino acid substitutions I38T and E23K in the influenza polymerase acidic (PA) protein lead to reduced susceptibility to the influenza antiviral drug baloxavir.
Paulina Koszalka +4 more
doaj +1 more source
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs [PDF]
, 2016 Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication ...
Berre, Stefano +16 more
core +4 more sources