, 2009 Antiviral agents are drugs approved in the USA by the Food and Drug Administration (FDA) for the treatment or control of viral infections. Available antiviral agents mainly target stages in the viral life cycle. The target stages in the viral life cycle are; viral attachment to host cell, uncoating, synthesis of viral mRNA, translation of mRNA ...
Paintsil, E., Cheng, Yung-Chi
openaire +2 more sources
Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]
, 2017 In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela +4 more
core +1 more source
Graphene‐Based Nanocomposites as Antibacterial, Antiviral and Antifungal Agents
Advanced Healthcare Materials, 2022 Over the past decade, there have been many interesting studies in the scientific literature about the interaction of graphene‐based polymeric nanocomposites with microorganisms to tackle antimicrobial resistance.
Seda Gungordu Er +2 more
semanticscholar +1 more source
Entecavir versus tenofovir in patients with chronic hepatitis B: Enemies or partners in the prevention of hepatocellular carcinoma [PDF]
Clinical and Molecular Hepatology, 2021 Over the past several decades, entecavir (ETV) and tenofovir disoproxil fumarate (TDF) have remained the first-line antiviral agents in several international guidelines.
Sung Won Lee +3 more
doaj +1 more source
Polyclonal and monoclonal B lymphocytes response in HCV-infected patients treated with direct-acting antiviral agents [PDF]
, 2017 Hepatitis C virus (HCV) chronic infection can be associated with extrahepatic manifestations such as mixed cryoglobulinaemia and lymphoproliferative disorders that are endowed with increased rates of morbidity and all-cause mortality.
Burra, Patrizia +13 more
core +1 more source
Silver nanoparticles as potential antiviral agents against African swine fever virus
Materials Research Express, 2020 African swine fever virus (ASFV) is the cause of a highly contagious and fatal disease in domestic swine, but no vaccine or effective medicine is available so far, therefore, looking for a novel and effective anti-ASFV agent is a very imperative mission.
Tran Thi Ngoc Dung +7 more
semanticscholar +1 more source
Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. [PDF]
, 2007 BackgroundWe reported previously on the emergence and clinical implications of simian immunodeficiency virus (SIVmac251) mutants with a K65R mutation in reverse transcriptase (RT), and the role of CD8+ cell-mediated immune responses in suppressing ...
Bischofberger, Norbert +10 more
core +3 more sources
Broad‐Spectrum Antiviral Agents Based on Multivalent Inhibitors of Viral Infectivity
Advanced Healthcare Materials, 2021 The ongoing pandemic of the coronavirus disease (Covid‐19), caused by the spread of the severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2), highlights the need for broad‐spectrum antiviral drugs.
A. Zelikin, F. Stellacci
semanticscholar +1 more source
Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]
, 2011 A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W. +2 more
core +2 more sources
Medicinal Plants as Effective Antiviral Agents and Their Potential Benefits
Natural Product CommunicationsThis paper explores a diverse field of medicinal plants as potential antiviral agents, and delves into utilization of plant medicine for combating viral infections, emphasizing recent surge in research on natural products from plants as antiviral agents.
G. Atampugbire +2 more
semanticscholar +1 more source