Antimicrobial-resistant infections are an urgent public health threat, and development of novel antimicrobial therapies has been painstakingly slow. Polymicrobial infections are increasingly recognized as a significant source of severe disease and also ...
Jeffrey A. Melvin+6 more
doaj +1 more source
: Objectives: As a host restriction factor, apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3G) has been shown to suppress the replication of several viruses including hepatitis B virus (HBV).
Jin Hu+6 more
doaj
Can biopolymers act as antiviral agents?
editorial
J. Seppala, S. Borandeh
doaj +1 more source
First Principle Simulation of Coated Hydroxychloroquine on Ag, Au and Pt Nanoparticle as a Potential Candidate for Treatment of SARS-CoV-2 (COVID-19) [PDF]
The {\it{in vitro}} antiviral activity of Hydroxychloroquine (HCQ) and chloroquine (CQ) against SARS-CoV-2 from the first month of pandemic proposed these drugs as the appropriate therapeutic candidate, although their side effect directed the clinical test toward optimizing the safe utilization strategies.
arxiv +1 more source
Coumarin: An emerging antiviral agent [PDF]
Viral infections are responsible for many illnesses, and recent outbreaks have raised public health concerns. Despite the availability of many antiviral drugs, they are often unsuccessful due to the generation of viral mutants and less effective against their target virus.
Siddharth Manvati+2 more
openaire +4 more sources
Complexes of Ruthenium(II) as Promising Dual-Active Agents against Cancer and Viral Infections
Poor responses to medical care and the failure of pharmacological treatment for many high-frequency diseases, such as cancer and viral infections, have been widely documented.
Assunta D’Amato+6 more
doaj +1 more source
Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]
In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela+4 more
core +1 more source
SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways [PDF]
The SARS-CoV-2 coronavirus, the etiologic agent responsible for COVID-19 coronavirus disease, is a global threat. To better understand viral tropism, we assessed the RNA expression of the coronavirus receptor, ACE2, as well as the viral S protein priming protease TMPRSS2 thought to govern viral entry in single-cell RNA-sequencing (scRNA-seq) datasets ...
arxiv +1 more source
Update on therapeutic options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source
Graphene‐Based Nanocomposites as Antibacterial, Antiviral and Antifungal Agents
Over the past decade, there have been many interesting studies in the scientific literature about the interaction of graphene‐based polymeric nanocomposites with microorganisms to tackle antimicrobial resistance.
Seda Gungordu Er+2 more
semanticscholar +1 more source