Results 61 to 70 of about 3,701,075 (393)

Antiviral Activity of Anthranilamide Peptidomimetics against Herpes Simplex Virus 1 and a Coronavirus

Antibiotics, 2023
The development of potent antiviral agents is of utmost importance to combat the global burden of viral infections. Traditional antiviral drug development involves targeting specific viral proteins, which may lead to the emergence of resistant strains ...
Umme Laila Urmi, Samuel Attard, Ajay Kumar Vijay, Mark D. P. Willcox, Naresh Kumar, Salequl Islam, Rajesh Kuppusamy   +6 more
doaj   +1 more source

Medicinal chemistry strategies toward host targeting antiviral agents

Medicinal research reviews (Print), 2020
Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and have been demonstrated to be very successful in combating viral infections in clinic.
Xingyue Ji, Zhuorong Li
semanticscholar   +1 more source

Role of antiviral therapy in the natural history of hepatitis B virus-related chronic liver disease [PDF]

, 2015
Hepatitis B virus (HBV) infection is a dynamic state of interactions among HBV, hepatocytes, and the host immune system. Natural history studies of chronic hepatitis B (CHB) infection have shown an association between active viral replication and adverse
Farinati, Fabio, Gottardo, G, Rodr\uedguez Castro, K, Russo, FRANCESCO PAOLO, Scribano, L, Vanin, V   +5 more
core   +1 more source

Plant-Derived Antimicrobial Peptides as Potential Antiviral Agents in Systemic Viral Infections

Pharmaceuticals, 2021
Numerous studies have led to a better understanding of the mechanisms of action of viruses in systemic infections for the development of prevention strategies and very promising antiviral therapies.
Nour Mammari, Ysaline Krier, Quentin Albert, M. Devocelle, M. Varbanov, On Behalf Of The Oemonom   +5 more
semanticscholar   +1 more source

Inhibition of Enveloped Virus Surrogate Phi6 Infection Using Yeast-Derived Vacuoles

Microbiology Spectrum, 2023
The periodic emergence of infectious disease poses a serious threat to human life. Among the causative agents, including pathogenic bacteria and fungi, enveloped viruses have caused global pandemics.
Wooil Choi, Yang-Hoon Kim, Jiho Min
doaj   +1 more source

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)

Viruses, 2020
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion in treatment options. In this study, we investigated the anti-SARS-CoV-2 activities of
Shuofeng Yuan, Chris Chun-Yiu Chan, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Ronghui Liang, Jianli Cao, Kaiming Tang, Jian-Piao Cai, Zi-Wei Ye, Feifei Yin, Kelvin Kai-Wang To, Hin Chu, Dong-Yan Jin, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Jasper Fuk-Woo Chan   +15 more
doaj   +1 more source

Comparative Performance Evaluation of Personal Protective Measures and Antiviral Agents Against SARS-CoV-2 Variants: A Narrative Review

Clinical Pathology, 2023
Scientists identified SARS-CoV-2 in December 2019 in Wuhan city of China. Soon after its identification, Covid-19 spreads almost everywhere. The World Health Organization (WHO) declared the Covid-19 outbreak as a pandemic on March 11, 2020. Countries are
Md Anamul Haque, Md Tanbir, Bulbul Ahamed, Md Jamal Hossain, Arpita Roy, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan, Md Rabiul Islam   +7 more
doaj   +1 more source

Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals. [PDF]

, 2007
BackgroundThe SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo.
A Adachi, A Valentin, April N. Kinkade, Barbara Sloan, BD Jamieson, BD Jamieson, BK Berges, BS Robinson, CA Stoddart, CA Stoddart, CA Stoddart, Cheryl A. Bales, Cheryl A. Stoddart, E De Clercq, ED Miller, EJ Freireich, ES Withers-Ward, G Kovalev, George Chkhenkeli, GM Aldrovandi, GM Aldrovandi, GM Aldrovandi, H Kaneshima, H Kaneshima, J McCune, J Mordenti, Jennifer C. Bare, JF Krowka, JM McCune, JM McCune, JM McCune, JM McCune, JM Strizki, José M. Rivera, JY Feng, L Rabin, L Su, L Su, L Zhang, Linqi Zhang, LT Rimsky, M Markowitz, Mary E. Moreno, ME Keir, MG Manz, ML Bonyhadi, ML Greenberg, Paul L. Black, PS Koka, R Datema, R Namikawa, R Namikawa, RC Bast, RD Berkowitz, RD Berkowitz, RD Berkowitz, RD Berkowitz, RG Amado, Rollie E. Ronquillo, S Baenziger, S Gartner, S Gorantla, SD Young, SG Kitchen, SG Kitchen, SK Stanley, Sofiya A. Galkina, Z Sun   +67 more
core   +4 more sources

Silver Nanoparticles as Potential Antiviral Agents

Molecules, 2011
Virus infections pose significant global health challenges, especially in view of the fact that the emergence of resistant viral strains and the adverse side effects associated with prolonged use continue to slow down the application of effective ...
Massimiliano Galdiero, Veronica Marra, Marco Cantisani, Mariateresa Vitiello, Stefania Galdiero, Annarita Falanga   +5 more
doaj   +1 more source

Effect of antiviral therapy in reducing perinatal transmission of hepatitis B virus and maternal outcomes after discontinuing them [PDF]

Clinical and Molecular Hepatology, 2018
Background/Aims There have been numerous efforts to reduce mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with antiviral agents during pregnancy.
Kwang Il Seo, Si Hyun Bae, Pil Soo Sung, Chung-Hwa Park, Hae Lim Lee, Hee Yeon Kim, Hye Ji Kim, Bo Hyun Jang, Jeong Won Jang, Seung Kew Yoon, Jong Young Choi, In-Yang Park, Juyoung Lee, Hyun Seung Lee, Sa-Jin Kim, Jung Hyun Kwon, U Im Chang, Chang Wook Kim, Se Hyun Jo, Young Lee, Fisseha Tekle, Jong-Hyun Kim   +21 more
doaj   +1 more source