Viruses, 2020 The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion in treatment options. In this study, we investigated the anti-SARS-CoV-2 activities of
Shuofeng Yuan +15 more
doaj +1 more source
Drop-out rate from the liver transplant waiting list due to HCC progression in HCV-infected patients treated with direct acting antivirals. [PDF]
, 2017 BACKGROUND & AIM: concerns about an increased hepatocellular carcinoma (HCC) recurrence rate following directly acting antiviral (DAA) therapy in cirrhotic patients with a prior complete oncological response have been raised. Data regarding the impact of
Angeli, Paolo +16 more
core +1 more source
Broad‐Spectrum Antiviral Agents Based on Multivalent Inhibitors of Viral Infectivity
Advanced Healthcare Materials, 2021 The ongoing pandemic of the coronavirus disease (Covid‐19), caused by the spread of the severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2), highlights the need for broad‐spectrum antiviral drugs.
A. Zelikin, F. Stellacci
semanticscholar +1 more source
Clinical Pathology, 2023 Scientists identified SARS-CoV-2 in December 2019 in Wuhan city of China. Soon after its identification, Covid-19 spreads almost everywhere. The World Health Organization (WHO) declared the Covid-19 outbreak as a pandemic on March 11, 2020. Countries are
Md Anamul Haque +7 more
doaj +1 more source
Inhibition of Enveloped Virus Surrogate Phi6 Infection Using Yeast-Derived Vacuoles
Microbiology Spectrum, 2023 The periodic emergence of infectious disease poses a serious threat to human life. Among the causative agents, including pathogenic bacteria and fungi, enveloped viruses have caused global pandemics.
Wooil Choi, Yang-Hoon Kim, Jiho Min
doaj +1 more source
The efficacy of antiviral drug, HIV viral load and the immune response [PDF]
arXiv, 2021 Developing antiviral drugs is an exigent task since viruses mutate to overcome the effect of antiviral drugs. As a result, the efficacy of most antiviral drugs is short-lived. To include this effect, we modify the Neumann and Dahari model. Considering the fact that the efficacy of the antiviral drug varies in time, the differential equations introduced
arxiv
Synthesis and regioselective N- and O-alkylation of 3-alkyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones and 2-phenyl-9-propyl-9H-purin-6(1H)-one with evaluation of antiviral and antitumor activities [PDF]
, 2008 3-Alkyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones were prepared by nitrosative cyclization of the appropriate 5,6-diamino-2-phenylpyrimidin-4(3H)-ones with nitrous acid and were subjected to regioselective alkylation with several alkylating ...
Ali +34 more
core +1 more source
Silver Nanoparticles as Potential Antiviral Agents
Molecules, 2011 Virus infections pose significant global health challenges, especially in view of the fact that the emergence of resistant viral strains and the adverse side effects associated with prolonged use continue to slow down the application of effective ...
Massimiliano Galdiero +5 more
doaj +1 more source
Effect of antiviral therapy in reducing perinatal transmission of hepatitis B virus and maternal outcomes after discontinuing them [PDF]
Clinical and Molecular Hepatology, 2018 Background/Aims There have been numerous efforts to reduce mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with antiviral agents during pregnancy.
Kwang Il Seo +21 more
doaj +1 more source
Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents [PDF]
, 2014 Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes.
A Owsianka +72 more
core +6 more sources