Results 131 to 140 of about 75,063 (251)

TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu, Ling‐Jung Yen, Hui‐Ling Hsia, Zi‐Xeng Weng, Chi‐Hsiang Chung, Paul Wei‐Che Hsu, Chih‐Wei Chiu, Wu‐Chien Chien, Tsung‐Hsien Chang   +8 more
wiley   +1 more source

Unraveling the layers of epigenetic control in respiratory antiviral defense. [PDF]

J Virol
McFadden MI, Simo B, Forero A.
europepmc   +1 more source

Innate immune sensing of alphavirus chikungunya: balancing antiviral defense and pathogenesis. [PDF]

Front Immunol
da Silva JSF, Ferreira Junior CV, Dos Santos LMS, de Andrade-Neto VF, Guedes PMDM, Yaochite JNU, França RFO, Brito RMM, Nascimento MSL.   +8 more
europepmc   +1 more source

The multidimensional significance of virus-host protein interactions and their implications in the antiviral defense of plants. [PDF]

Stress Biol
Zhang J, Qi C, Wu Z, Zhang Y, Shi J, Li Z, Guo J, Zhou X, Tang S, Yang J, Liu P.   +10 more
europepmc   +1 more source

Debneyol decoded: A metabolic organizer powers broad‐spectrum plant defense

New Plant Protection, EarlyView.
Abstract A new Cell study by Wang et al. resolves the long‐elusive biosynthesis and regulation of debneyol, a fungicidal sesquiterpenoid phytoalexin in Solanaceae. The authors define the complete three‐step route from farnesyl pyrophosphate to debneyol and identify the small protein MCD1 as a metabolic organizer that assembles a multienzyme complex to ...
Shaojie Han
wiley   +1 more source

MAVS is important for antiviral defense against influenza A virus in a human respiratory epithelium model. [PDF]

PLoS One
Hemberg M, Hansen AL, Storgaard J, Blay-Cadanet J, Pedersen A, Thielke AL, Holm CK.   +6 more
europepmc   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

USP39 promotes antiviral defense through post-transcriptional control of RIG-I and stabilization of STING. [PDF]

PLoS Biol
Quan J, Zhao X, Chen S, Li H, Chen W, Di Q, Li X, Zhao J, Wu H, Chen J, Xiao Y, Wu Z, Chen W.   +12 more
europepmc   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Far-red light orchestrates antiviral defense in plants. [PDF]

Sci Adv
Gong Q, He L, Huang F, Wang Y, Xie J, Hong Y, Liu Y.   +6 more
europepmc   +1 more source