Results 221 to 230 of about 951,212 (251)

Correction: Genome-wide CRISPR/Cas9 screening identifies host factors critical for antiviral defense against equine herpesvirus type 1. [PDF]

Front Immunol
Li Z, Ge L, Yu T, Lv S, Fu Q, Shi H.
europepmc   +1 more source

Advances in Cytosolic dsRNA Sensing of Viral Infections

Immunology &Cell Biology, EarlyView.
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley   +1 more source

Immunity hubs orchestrating antiviral defense. [PDF]

Cell Res
Zhu L, Zhang Z.
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Antiviral defense against filovirus infections: targets and evasion mechanisms. [PDF]

Future Microbiol
Bodmer BS, Wendt L, Dupré J, Groseth A, Hoenen T.   +4 more
europepmc   +1 more source

MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions

Immunology, EarlyView.
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula, Saurabh Mishra, Pugazhendhi Kannan, Annette Bellar, Amy Attaway, Nicole Welch, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Dual effects of the alternative spliced RIG-I isoform PTIR1 on host antiviral defense and immune homeostasis. [PDF]

Cell Death Dis
Song J, Tian W, Liu L, Zhao X, Zhao W, Lu D.   +5 more
europepmc   +1 more source

Efficacy of Ccombody as an Immunoprophylaxis Strategy: Impact on Immune Gene Expression of Pacific White Shrimp (Penaeus vannamei) Against Acute Hepatopancreatic Necrosis Disease (AHPND)

Journal of Fish Diseases, EarlyView.
ABSTRACT Acute hepatopancreatic necrosis disease (AHPND) is caused by a plasmid bearing strain of Vibrio parahaemolyticus (VpAHPND), which produces PirA and PirB toxins that specifically target and damage hepatopancreatic and epithelial cells of the shrimp gastrointestinal tract.
Prawporn Thaijongrak, Kasemsuk Kitisriworapun, Theerapat Damrongsakul, Napat Huttayanan, Thitipan Juntong, Andrew P. Shinn, Tae Sung Jung, Surasak Jittakhot, Wanna Sirimanapong   +8 more
wiley   +1 more source

Type I Interferons in SARS-CoV-2 Cutaneous Infection: Is There a Role in Antiviral Defense? [PDF]

Int J Mol Sci
Yendo TM, Orfali RL, Pereira NV, Pereira NZ, Ramos YÁL, Kawakami JT, Duarte-Neto AN, Sotto MN, Silva LFF, Duarte AJDS, Sato MN, Aoki V.   +11 more
europepmc   +1 more source

Host-virus molecular arms race: RNAi-mediated antiviral defense and viral suppressor of RNAi. [PDF]

Cell Insight
Zhang B, Zhou X, Ren Y.
europepmc   +1 more source