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Antiviral Drugs in Influenza [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2022
Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appeared on the market.
Magdalena Świerczyńska   +2 more
openaire   +3 more sources

Antiviral Drugs for EBV [PDF]

open access: yesCancers, 2018
Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35–50% cases when infection occurs during adolescence and early adulthood.
Pagano, Joseph S.   +2 more
openaire   +4 more sources

Pharmacology of Antiviral Drugs [PDF]

open access: yesViruses
Antiviral drug therapy has significantly evolved over the past four decades, partly driven by improved understanding of viral replication mechanisms but also advances in pharmacology and formulation technologies [...]
David E. Martin
doaj   +2 more sources

Antiviral drugs–

open access: green, 2012
Stephen N.J. Korsman   +4 more
  +5 more sources

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results

open access: yesNew England Journal of Medicine, 2020
Background World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19 ...
H. Pan   +73 more
semanticscholar   +2 more sources

Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs

open access: yesClinical Infectious Diseases, 2022
At a crucial time with rapid spread of Omicron SARS-CoV-2 virus variant globally, the United States Food and Drug Administration has issued an emergency use authorization for two oral antivirals molnupiravir (>18 years) and nirmatrelvir-ritonavir ...
L. Saravolatz   +2 more
semanticscholar   +1 more source

Hyperbranched Polymers: Recent Advances in Photodynamic Therapy against Cancer

open access: yesPharmaceutics, 2023
Hyperbranched polymers are a class of three-dimensional dendritic polymers with highly branched architectures. Their unique structural features endow them with promising physical and chemical properties, such as abundant surface functional groups ...
Jie Chen, Yichuan Zhang
doaj   +1 more source

Bacteria exposed to antiviral drugs develop antibiotic cross-resistance and unique resistance profiles

open access: yesCommunications Biology, 2023
Bacteria exposed to antiviral drugs in vitro can develop multiple resistance mutations that confer cross-resistance to antibiotics. Antiviral drugs are used globally as treatment and prophylaxis for long-term and acute viral infections.
Veronica J. Wallace   +3 more
semanticscholar   +1 more source

A review: Mechanism of action of antiviral drugs

open access: yesInternational Journal of Immunopathology and Pharmacology, 2021
Antiviral drugs are a class of medicines particularly used for the treatment of viral infections. Drugs that combat viral infections are called antiviral drugs. Viruses are among the major pathogenic agents that cause number of serious diseases in humans,
S. Kausar   +9 more
semanticscholar   +1 more source

Regulation of N6-methyladenosine (m6A) RNA methylation in microglia-mediated inflammation and ischemic stroke

open access: yesFrontiers in Cellular Neuroscience, 2022
N6-methyladenosine (m6A) is the most abundant post-transcription modification, widely occurring in eukaryotic mRNA and non-coding RNA. m6A modification is highly enriched in the mammalian brain and is associated with neurological diseases like Alzheimer ...
Fangfang Zhang   +5 more
doaj   +1 more source

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