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Antiviral Drugs in Influenza [PDF]
Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appeared on the market.
Magdalena Świerczyńska +2 more
openaire +3 more sources
Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35–50% cases when infection occurs during adolescence and early adulthood.
Pagano, Joseph S. +2 more
openaire +4 more sources
Pharmacology of Antiviral Drugs [PDF]
Antiviral drug therapy has significantly evolved over the past four decades, partly driven by improved understanding of viral replication mechanisms but also advances in pharmacology and formulation technologies [...]
David E. Martin
doaj +2 more sources
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
Background World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19 ...
H. Pan +73 more
semanticscholar +2 more sources
Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs
At a crucial time with rapid spread of Omicron SARS-CoV-2 virus variant globally, the United States Food and Drug Administration has issued an emergency use authorization for two oral antivirals molnupiravir (>18 years) and nirmatrelvir-ritonavir ...
L. Saravolatz +2 more
semanticscholar +1 more source
Hyperbranched Polymers: Recent Advances in Photodynamic Therapy against Cancer
Hyperbranched polymers are a class of three-dimensional dendritic polymers with highly branched architectures. Their unique structural features endow them with promising physical and chemical properties, such as abundant surface functional groups ...
Jie Chen, Yichuan Zhang
doaj +1 more source
Bacteria exposed to antiviral drugs in vitro can develop multiple resistance mutations that confer cross-resistance to antibiotics. Antiviral drugs are used globally as treatment and prophylaxis for long-term and acute viral infections.
Veronica J. Wallace +3 more
semanticscholar +1 more source
A review: Mechanism of action of antiviral drugs
Antiviral drugs are a class of medicines particularly used for the treatment of viral infections. Drugs that combat viral infections are called antiviral drugs. Viruses are among the major pathogenic agents that cause number of serious diseases in humans,
S. Kausar +9 more
semanticscholar +1 more source
N6-methyladenosine (m6A) is the most abundant post-transcription modification, widely occurring in eukaryotic mRNA and non-coding RNA. m6A modification is highly enriched in the mammalian brain and is associated with neurological diseases like Alzheimer ...
Fangfang Zhang +5 more
doaj +1 more source

