In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]
, 2007 International ...
Croubels, Siska +6 more
core +3 more sources
, 2010 This chapter discusses the adverse effects of antiviral drugs used against cytomegalovirus, herpesviruses, hepatitis viruses, against HIV, and against influenza viruses. The cidofovir, drug active against cytomegalovirus, has been associated with bronchiolitis obliterans. Aciclovir and valaciclovir has been reported with renal insufficiency. Adefovir ,
Armando M. De Palma, Johan Neyts
+4 more sources
Key Regulators of Autophagosome Closure
Cells, 2021 Autophagy is an evolutionarily conserved pathway, in which cytoplasmic components are sequestered within double-membrane vesicles called autophagosomes and then transported into lysosomes or vacuoles for degradation.
Wenyan Jiang +6 more
doaj +1 more source
Modeling the Worldwide Spread of Pandemic Influenza: Baseline Case and Containment Interventions [PDF]
, 2007 We present a study of the worldwide spread of a pandemic influenza and its possible containment at a global level taking into account all available information on air travel.
Alain Barrat +5 more
core +5 more sources
Modeling viral infectious diseases and development of antiviral therapies using human induced pluripotent stem cell-derived systems [PDF]
, 2015 The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Barzon, Luisa +6 more
core +2 more sources
Hepatitis C virus pharmacogenomics in Latin American populations: implications in the era of direct-acting antivirals [PDF]
, 2017 In recent years, great progress has been made in the field of new therapeutic options for hepatitis C virus (HCV) infection. The new direct-acting antiviral agents (DAAs) represent a great hope for millions of chronically infected individuals because ...
Caputo, Mariela +4 more
core +1 more source
Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]
, 2017 Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N +4 more
core +3 more sources
Antiviral Drugs Against Severe Fever With Thrombocytopenia Syndrome Virus Infection
Frontiers in Microbiology, 2020 Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by SFTS virus (SFTSV), which is a novel bunyavirus.
Mutsuyo Takayama-Ito, M. Saijo
semanticscholar +1 more source
Variability in antifungal and antiviral use in hospitalized children [PDF]
, 2017 We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S +6 more
core +2 more sources
How to Discover Antiviral Drugs Quickly.
New England Journal of Medicine, 2020 Dynamic Developments in Screening Candidate Drugs Molecular-dynamics simulations together with virtual high-throughput screening provide a means of quick evaluation of existing drugs for antiviral ...
Jerry M. Parks, Jeremy C. Smith
semanticscholar +1 more source