Results 41 to 50 of about 4,215,496 (299)

Antiviral drug resistance

BMJ, 1998
The development of effective antiviral drugs is an important biomedical scientific achievement of the late 20th century. Highly potent drugs are now available against herpes viruses, HIV, hepatitis B virus, and influenza virus. This list will extend to papillomaviruses, respiratory viruses, enteroviruses, and hepatitis C virus over the next 5-10 years.
D, Pillay, M, Zambon
openaire   +3 more sources

Potential Antiviral Drugs for SARS-Cov-2 Treatment: Preclinical Findings and Ongoing Clinical Research.

In Vivo, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), initially termed 2019-new CoV (2019-nCoV), is a novel coronavirus responsible for the severe respiratory illness currently ongoing worldwide from the beginning of December 2019. This beta gene
S. Bimonte, A. Crispo, A. Amore, E. Celentano, A. Cuomo, M. Cascella   +5 more
semanticscholar   +1 more source

Predicting commercially available antiviral drugs that may act on the novel coronavirus (2019-nCoV), Wuhan, China through a drug-target interaction deep learning model

bioRxiv, 2020
The infection of a novel coronavirus found in Wuhan of China (2019-nCoV) is rapidly spreading, and the incidence rate is increasing worldwide. Due to the lack of effective treatment options for 2019-nCoV, various strategies are being tested in China ...
B. Beck, Bonggun Shin, Yoonjung Choi, Sungsoo Park, Keunsoo Kang   +4 more
semanticscholar   +1 more source

Adverse Effects of Glyphosate and Microcystin-LR on Fish Health: Evidence from Structural and Functional Impairments in Zebrafish Gills

Animals
Glyphosate (GLY) and microcystin-LR (MC-LR) frequently co-occur in natural water bodies. In this study, a subacute exposure test was conducted on zebrafish treated with 3.5 mg/L GLY and 35 μg/L MC-LR, individually and in combination, for 21 d to ...
Yidan Zhang, Han Hu, Linmei Song, Zhihui Liu, Junguo Ma, Xiaoyu Li   +5 more
doaj   +1 more source

In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]

, 2007
International ...
Croubels, Siska, De Backer, Patrick, Garré, Barbara, Nauwynck, Hans, NEYTS, J, NUGENT, J, VAN DER MEULEN, K   +6 more
core   +3 more sources

How to Discover Antiviral Drugs Quickly.

New England Journal of Medicine, 2020
Dynamic Developments in Screening Candidate Drugs Molecular-dynamics simulations together with virtual high-throughput screening provide a means of quick evaluation of existing drugs for antiviral ...
Jerry M. Parks, Jeremy C. Smith
semanticscholar   +1 more source

Influenza A nucleoprotein binding sites for antivirals: current research and future potential [PDF]

, 2014
This document is the Accepted Manuscript version of the following article: Andreas Kukol and Hershna Patel, ‘Influenza A nucleoprotein binding sites for antivirals: current research and future potential’, Future Biology, Vol 9(7): 625-627, July 2014. The
Kukol, A, Kukol, A, Patel, H., Patel, H.
core   +2 more sources

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2020 Recommendations of the International Antiviral Society-USA Panel.

Journal of the American Medical Association (JAMA), 2020
Importance Data on the use of antiretroviral drugs, including new drugs and formulations, for the treatment and prevention of HIV infection continue to guide optimal practices.
M. Saag, R. Gandhi, J. Hoy, R. Landovitz, M. Thompson, P. Sax, Davey M. Smith, C. Benson, S. Buchbinder, C. del Rio, J. Eron, G. Fätkenheuer, H. Günthard, J. Molina, D. M. Jacobsen, P. Volberding   +15 more
semanticscholar   +1 more source

Dynamic alterations of oral fungal microbiota in Omicron infected patients

Scientific Reports
Oral fungal microbiota plays an important role in many diseases, however, the role of oral fungal microorganisms in the development of patients infected with Omicron has not been reported. A total of 963 tongue coating samples were prospectively included
Yarong Ma, Shanshuo Liu, Guizhen Zhang, Liwen Liu, Junyi Sun, Yawen Zou, Ying Sun, Lei Li, Benchen Rao, Haiyu Wang, Zujiang Yu, Zhigang Ren   +11 more
doaj   +1 more source

Modeling long-term longitudinal HIV dynamics with application to an AIDS clinical study

, 2009
A virologic marker, the number of HIV RNA copies or viral load, is currently used to evaluate antiretroviral (ARV) therapies in AIDS clinical trials. This marker can be used to assess the ARV potency of therapies, but is easily affected by drug exposures,
Huang, Yangxin, Lu, Tao
core   +1 more source