Results 61 to 70 of about 89,248 (335)

Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]

open access: yes, 2014
IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve   +4 more
core   +1 more source

Synthesis of Multi‐Substituted β‐Carbolin‐1‐ones via Iridium‐Catalyzed Intramolecular C─H/N─H Amination of 3‐Amino‐2‐pyridones

open access: yesAsian Journal of Organic Chemistry, EarlyView.
A method for the synthesis of multi‐substituted β‐carbolin‐1‐ones is developed, utilizing iridium‐catalyzed intramolecular C─H/N─H amination of 3‐amino‐2‐pyridones synthesized via the conjugate addition of diethyl 2‐aminomalonate to alkynyl imines.
Honoka Mori   +4 more
wiley   +1 more source

Lateral habenula regulates temporal pattern organization of rat exploratory behavior and acute nicotine-induced anxiety in hole board [PDF]

open access: yes, 2013
Nicotine is one of the most addictive drugs of abuse. Tobacco smoking is a major cause of many health problems worldwide, and is the first preventable cause of death.
Benigno, Arcangelo   +12 more
core  

Behavioral Profiles of Genetically Selected Aggressive and Nonaggressive Male Wild House Mice in Two Anxiety Tests [PDF]

open access: yes, 2000
Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light–dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for ...
Hof, Maleen,   +6 more
core   +2 more sources

Visible Light‐Mediated Preparation of a Key Intermediate Employed in the Synthesis of Zolpidem and Several Analogs

open access: yesChemistry – An Asian Journal, EarlyView.
A new visible light‐induced method is reported for the C3‐alkylation of imidazo[1,2‐a]pyrimidines and ‐pyridines with aryldiazoacetates. This protocol can be performed in open air and serves as a convenient entry to several known and new molecules. A formal synthesis of zolpidem is achieved by changing the alkylating agent to an appropriate hypervalent
Ronei M. S. Souza   +6 more
wiley   +1 more source

Pregabalin effects on neural response to emotional faces

open access: yesFrontiers in Human Neuroscience, 2012
Pregabalin has shown promise in the treatment of anxiety disorders. Previous functional magnetic resonance imaging (fMRI) studies indicate agents used to treat anxiety, e.g.
Robin Leora Aupperle   +9 more
doaj   +1 more source

Pharmacological effect of one icv dose of Allopregnanolone in female rat: behavioural profile [PDF]

open access: yes, 2015
We have previously observed that intracerebroventricular allopregnanolone (ALLO) injection produced an anxiolytic effect and inhibited sexual receptivity when the test was performed in a separate manner. Also, ALLO reverts learning deficit in female rats
Cabrera Kreiker, Ricardo Jorge   +5 more
core  

Implementing physician‐led medication reviews for patients with diabetes and severe mental disorder: A randomized controlled trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Patients with severe mental disorder and diabetes may be exposed to inappropriate polypharmacy increasing the risk of side effects and drug interactions. Although medication reviews may facilitate short‐term deprescribing, they are not known to affect clinical outcomes.
Johan Frederik Mebus Meyer Christensen   +2 more
wiley   +1 more source

Developing the Inpatient Mental Health Pharmaceutical Assessment and Care Tool (IMPACT) for use by UK mental health pharmacy teams—a modified Delphi study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To develop an evidence‐ and consensus‐based patient prioritization tool for use by UK mental health inpatient pharmacy teams. Methods A modified‐Delphi technique was used to obtain experts' agreement on the content, design and practical use of the patient prioritization tool.
Fatima Q. Alshaikhmubarak   +3 more
wiley   +1 more source

Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]

open access: yes, 2019
Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
core   +1 more source

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