Results 71 to 80 of about 89,248 (335)
Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator [PDF]
, 2018 We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K+ channel, TREK-1, and we identified a hydroxycoumarin-related compound, ostruthin, as an activator of this channel ...
Joseph, Ancy +3 more
core +2 more sources
Chemistry &Biodiversity, EarlyView.ABSTRACT Benzodiazepines are widely used in the treatment of anxiety, but their use may be interrupted due to side effects. This study evaluated the indole alkaloids isocarapanaubine (indole alkaloid 1 [AIN1]) and 18‐β‐hydroxy‐3‐epi‐α‐yohimbine (indole alkaloid 2 [AIN2]), extracted from Rauvolfia ligustrina, in adult zebrafish.
Nádia Aguiar Portela Pinheiro +10 more
wiley +1 more source
Veterinary EvidenceThe original article was published in Veterinary Evidence Vol 9, Issue 1 (2024): https://doi.org/10.18849/ve.v9i1.679 In the original version of the article the contributions of one of the authors, Christopher Minami, were listed as "Investigation ...
Olivia Williamson +5 more
doaj +1 more source
A meta-analysis of pharmacotherapy for social anxiety disorder: an examination of efficacy, moderators, and mediators [PDF]
, 2017 INTRODUCTION: Social anxiety disorder (SAD) is among the most prevalent mental disorders, associated with impaired functioning and poor quality of life. Pharmacotherapy is the most widely utilized treatment option.
Borenstein M +8 more
core +2 more sources
Cannabinoids From Trema micranthum (L.) Blume (Cannabaceae): A Cannabinoid Profiling System
Chemistry &Biodiversity, EarlyView.ABSTRACT Trema micranthum (L.) Blume is a species from the Cannabaceae botanical family, present all over the tropics. A recent study conducted by our group identified the presence of cannabidiol (CBD), Δ9‐tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinolic acid‐A in T. micranthum extracts.
Yasmin Cunha‐Silva +7 more
wiley +1 more source
FoodsDue to the health benefits of polyphenols and dietary fiber in combating mental disorders, we hypothesized that a polyphenol- and dietary fiber-enriched soup (RJ6601) would improve mental wellness in a rat model of middle-aged women.
Rujikan Chaisanam +4 more
doaj +1 more source
Maxillary nerve block: A comparison between the greater palatine canal and high tuberosity approaches. [PDF]
, 2018 Aim: Analgesia and anxiolysis during dental procedures are important for dental care and patient compliance. This study aims to compare two classical maxillary nerve block (MNB) techniques: the greater palatine canal (GPC) and the high tuberosity (HT ...
Bacci, C +6 more
core
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Antinociceptive and Anti‐inflammatory Effect of Nicandrin B Isolated From Datura ferox in Zebrafish
Chemistry &Biodiversity, EarlyView.ABSTRACT Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects in adult zebrafish (Danio rerio). Animals treated with Nic B (4, 20, and 40 mg/kg) showed no toxicity and maintained normal locomotor activity.
Jéssica Bezerra Maciel +15 more
wiley +1 more source
ChemBioChem, EarlyView.Both (−)‐ and (+)‐cannabidiol (CBD and ent‐CBD, respectively) are synthesized via a highly diastereoselective CSA‐catalyzed Friedel–Crafts reaction. ent‐CBD exhibits anxiolytic‐like effects in aged male mice without impairing long‐term memory formation.
Marcos Accioly Jr +4 more
wiley +1 more source