Results 81 to 90 of about 89,248 (335)

Neuropharmacological effects of the aqueous leaf extract and fractions of Pavetta crassipes (K. Schum) Rubiaceae in mice [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2017
Context: In Northern Nigeria, Pavetta crassipes (K. Schum) Rubiaceae leaf extracts are used in the treatment of convulsion, pain and mental illness; however, there is paucity of information on its neuropharmacological effects.
Moses W. Bariweni, Raymond I. Ozolua
doaj  

Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age

open access: yesFrontiers in Immunology, 2018
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a compound that does not produce the typical subjective effects of marijuana.Objectives: The aim of the present review is to describe the main advances in the development
José A. Crippa   +7 more
doaj   +1 more source

Reaction of N,N-Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions. [PDF]

open access: yes, 2018
A large number of clinically used drugs and experimental pharmaceuticals possess the N,N-dimethyltryptamine (DMT) structural core. Previous reports have described the reaction of this motif with dichloromethane (DCM), a common laboratory solvent used ...
Dunlap, Lee E, Olson, David E
core   +3 more sources

Predictors of Anorexia Nervosa and Obsessive‐Compulsive Disorder Comorbidity and Order of Diagnosis in a Danish National Cohort

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) and obsessive‐compulsive disorder (OCD) are highly comorbid; however, limited research has examined etiological pathways specific to individuals with AN developing OCD or individuals with OCD developing AN. This exploratory study aimed to identify factors influencing AN‐OCD comorbidity with a focus on the order ...
Lisa Yujia Zhu   +7 more
wiley   +1 more source

A Novel Application of Ketamine for Improving Perioperative Sleep Disturbances

open access: yesNature and Science of Sleep, 2021
Bijia Song, Junchao Zhu Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of ChinaCorrespondence: Junchao ZhuDepartment of Anesthesiology, Shengjing Hospital of China Medical University ...
Song B, Zhu J
doaj  

Nicotine : Pharmacology and therapeutic implications in neurodegenerative and psychiatric disorders [PDF]

open access: yes, 2005
The pathophysiology of tobacco-related diseases is complex and multifactorial. Among the various compounds in tobacco smoke are carcinogens such as nitrosamines, irritants such as a variety of phenolic compounds, volatiles such as carbon monoxide, and of
Scerri, Charles
core  

Comparing Outcomes for Telehealth Versus In‐Person Family‐Based Treatment: A Retrospective Chart Review

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Telehealth services have become part of many eating disorder (ED) treatment settings; yet, few studies have examined the effectiveness of family‐based treatment (FBT) delivered via telehealth. This study compared in‐person and telehealth FBT in rates of weight restoration, treatment completion, and metrics of treatment progress, and ...
Catherine R. Drury   +20 more
wiley   +1 more source

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes   +3 more
wiley   +1 more source

The impact of single‐dose trazodone administration on plasma endogenous adrenocorticotropic hormone and serum cortisol concentrations in healthy dogs

open access: yesJournal of Veterinary Internal Medicine
Background Conditions affecting the hypothalamic‐pituitary‐adrenal (HPA) axis are common in dogs. Testing the function of the HPA axis includes measurement of endogenous adrenocorticotropic hormone (eACTH) and performance of an adrenocorticotropic ...
Morgan Brown   +3 more
doaj   +1 more source

Efficacy of Adjunct Olanzapine Treatment in Adolescents With Anorexia Nervosa: A Comparison of Two Patient Cohorts

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background Anorexia nervosa (AN) is a severe psychiatric disorder with high mortality, requiring innovative treatment strategies. Olanzapine (OLZ), an atypical antipsychotic, has demonstrated efficacy in promoting weight gain and reducing psychopathological symptoms in adults with AN.
Helene Krauss   +10 more
wiley   +1 more source

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