Results 61 to 70 of about 16,952 (210)

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Effect of hyperlipidic diets on normal and abnormal aortic valves in the Syrian hamster: A preliminary study [PDF]

, 2015
Effect of hyperlipidic diets on normal and abnormal aortic valves in the Syrian hamster: A preliminary study. MC Fernández 1,2, J Moncayo-Arlandi 1, MT Soto 1, MA López-Unzu 1, B Fernández 1,2 and AC Durán 1,2.
Durán, Ana C., Fernández, Borja, Fernández, M.C., López-Unzu, Miguel Ángel, Moncayo-Arlandi, Javier, Soto, M. Teresa   +5 more
core  

Association between asymptomatic carotid atherosclerosis and degenerative aortic stenosis. [PDF]

, 2012
OBJECTIVE: Degenerative aortic stenosis shows similarities with atherosclerosis. To confirm the hypothesis that aortic stenosis is an "atherosclerosis-like" disease, we investigated the association between degenerative aortic stenosis and ...
FATTOUCH, Khalil, FERRO, Giovanni, Guarneri, FP, NOVO, Giuseppina, NOVO, Salvatore, RUSSO, Rosario   +5 more
core   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Vascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome [PDF]

, 2018
Background: Progerin, an aberrant protein that accumulates with age, causes the rare genetic disease Hutchinson-Gilford progeria syndrome (HGPS). Patients who have HGPS exhibit ubiquitous progerin expression, accelerated aging and atherosclerosis, and ...
Andrés Manzano, María J., Andrés, Vicente, Bentzon, Jacob F., Gonzalo, Pilar, Hamczyk, Magda Rita, López Otín, Carlos, Nogales, Paula, Villa Bellosta, Ricardo   +7 more
core   +4 more sources

Fetuin-A levels in association with calcific aortic valve disease: A meta-analysis

Atherosclerosis Plus, 2023
Background and aims: Calcific aortic valve disease (CAVD) is a common valvular disease, prevalent particularly within the older age groups. The potential use of biomarkers in diagnosing and assessing the severity of CAVD, in supplementation with imaging ...
Muhammad Omar Larik
doaj   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Involvement of proinflammatory S100A9/A8 in the atherocalcinosis of aortic valves [PDF]

, 2017
Згідно результатів Європейського дослідження серцевих вад (Euro-Heart Survey on Vascular Heart Disease), серед уражень серцевих клапанів найбільш поширеною патологією є неревматичний аортальний стеноз, який також називають кальцифікованим аортальним ...
Chernov, Y.O., Iashchishyn, Igor Olexandrovych, Morozova-Roche, L.A., Moskalenko, Roman Andriiovych, Piddubnyi, Artem Mykhailovych, Romaniuk, Anatolii Mykolaiovych, Zakorko, Inna-Margaryta Sergiyivna, Закорко, Инна Маргарита Сергеевна, Закорко, Інна-Маргарита Сергіївна, Москаленко, Роман Андреевич, Москаленко, Роман Андрійович, Поддубный, Артем Михайлович, Піддубний, Артем Михайлович, Романюк, Анатолий Николаевич, Романюк, Анатолій Миколайович, Ящишин, Игорь Александрович, Ящишин, Ігор Олександрович   +16 more
core   +1 more source

The association of hypertension and aortic valve sclerosis

Blood Pressure, 2005
Aortic valve sclerosis (AVS), a condition of thickening and calcification of the normal trileaflet aortic valve without the obstruction to left ventricular outflow, is likely the initial stage in the development of aortic stenosis and is associated with an increased incidence of cardiovascular events. The objective of this study is to critically review
openaire   +2 more sources

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source