Results 71 to 80 of about 574,230 (187)

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam   +4 more
wiley   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 1953-1972, September 2026.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll   +2 more
wiley   +1 more source

Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant

open access: yesFrontiers in Cardiovascular Medicine
BackgroundTuberous sclerosis complex (TSC) is a multisystem genetic disorder primarily characterized by the development of benign tumors in multiple organs.
Zhiqin Du   +7 more
doaj   +1 more source

Low flow low gradient aortic stenosis: clinical pathways

open access: yesIndian Heart Journal, 2014
Aortic stenosis patients with severe LV dysfunction and low cardiac output present with relatively low transvalvular gradients. It is difficult to distinguish them from aortic sclerosis and LV dysfunction with low cardiac output.
I. Sathyamurthy, K. Jayanthi
doaj   +1 more source

When Myocardial Injury in Lupus Is Not Lupus: Probable Antimalarial‐Associated Cardiomyopathy Mimicking Lupus Myocarditis

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Antimalarial cardiotoxicity may mimic lupus myocarditis in systemic lupus erythematosus. We report a 53‐year‐old woman with chronic antimalarial exposure, myocardial injury, biventricular dysfunction, electrical abnormalities, low lupus activity, and no myocardial edema.
Diego Armando Pérez Covo   +9 more
wiley   +1 more source

The Human PNPLA3I148M Polymorphism Alters the Renal Kinome and Transporters to Cause Hyperfiltration and Hypertension

open access: yesFASEB BioAdvances, Volume 8, Issue 9, September 2026.
The present study used mice carrying the I148M polymorphism in the human Patatin‐like phospholipase domain‐containing protein 3 (PNPLA3I148M) to determine the role of this polymorphism in regulating blood pressure and renal filtration. Kinome analysis revealed that male PNPLA3I148M mice exhibited decreased phosphorylation of protein kinase c alpha ...
Gertrude Arthur   +7 more
wiley   +1 more source

Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis [PDF]

open access: yesCardiovascular Research, 2013
Aortic valve sclerosis (AVSc) is a hallmark of several cardiovascular conditions ranging from chronic heart failure and myocardial infarction to calcific aortic valve stenosis (AVS). AVSc, present in 25-30% of patients over 65 years of age, is characterized by thickening of the leaflets with marginal effects on the mechanical proprieties of the valve ...
P. Poggio   +9 more
openaire   +2 more sources

Long-term Transcatheter Aortic Valve Durability [PDF]

open access: yes, 2019
Transcatheter aortic valve implantation (TAVI) has become the standard of care for high-risk and inoperable surgical patients and a valid alternative to surgery for low- and intermediate-risk patients with severe, symptomatic aortic stenosis.
Enrico Criscione   +4 more
core   +1 more source

Cardiovascular findings in classic homocystinuria

open access: yesMolecular Genetics and Metabolism Reports, 2020
Objective: describe cardiovascular findings from echocardiograms and electrocardiograms in patients with Classic Homocystinuria Methods: this retrospective exploratory study evaluated fourteen subjects with Classic Homocystinuria (median age = 27.3 years;
Marco Antônio Baptista Kalil   +5 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 8, August 2026.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy