Results 31 to 40 of about 2,749 (160)

Cardiovascular Imaging in Pregnancy: Valvulopathy, Hypertrophic Cardiomyopathy, and Aortopathy

Frontiers in Cardiovascular Medicine, 2022
Pregnancy is associated with profound hemodynamic changes that are particularly impactful in patients with underlying cardiovascular disease. Management of pregnant women with cardiovascular disease requires careful evaluation that considers the well ...
Haneen Ismail, Andrew J. Bradley, Jannet F. Lewis   +2 more
doaj   +1 more source

Obstetric considerations for aortopathy in pregnancy

Annals of Cardiothoracic Surgery, 2023
Aortic dissection (AD) associated with pregnancy can have catastrophic consequences for the mother and/or fetus. AD occurs in 4-5 per 1,000,000 pregnancies and, despite its rarity, is the third most frequent maternal cardiovascular cause of death. AD associated with pregnancy is most likely to occur in the third trimester or postpartum period.
Whelan, Anna R., Ringel, Myles E., Shalhub, Sherene, Russo, Melissa L.   +3 more
openaire   +2 more sources

A Retrospective Analysis of Human Angiotensin II Receptor Blockers (ARB) Pharmacokinetics, Dosages and Cmax Values for the Experimental Modelling of Pleiotropic and Supratherapeutic Activities

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.
ABSTRACT Angiotensin II (AngII) receptor blockers (ARBs) are medications that lower systolic blood pressure (BP) by antagonizing the AngII type 1 receptor (AT1). However, ARBs have documented or suspected therapeutic properties in diseases not caused by high BP including diabetes, muscular dystrophy, chronic obstructive pulmonary diseases (COPD) and ...
Alexandria Evans, Pascal Bernatchez
wiley   +1 more source

In vitro characterization of hemodynamics in bicuspid aortic valves: The impact of valve and ascending aortic morphologies

Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 411-429, January 2026.
Abstract Purpose This study investigated the effect of bicuspid aortic valve (BAV) morphology and ascending aortic curvature (AAAc) bending angles on aortic hemodynamics, focusing on transvalvular jets and secondary helical flows that contribute to systolic hemodynamic stress linked to aortic complications.
Kaoru Hattori, Natsuki Nakama, Jumpei Takada, Michinobu Nagao, Yasuhiro Goto, Hiroshi Niinami, Kiyotaka Iwasaki   +6 more
wiley   +1 more source

Bovine aortic arch with supravalvular aortic stenosis

Indian Heart Journal, 2016
A 5-year-old boy was diagnosed to have supravalvular aortic stenosis (SVAS). On evaluation of CT angiogram, there was associated bovine aortic arch (BAA).
Mohammed Idhrees, Vijay Thomas Cherian, Sabarinath Menon, Thomas Mathew, Baiju S. Dharan, K. Jayakumar   +5 more
doaj   +1 more source

Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study

Türk Kardiyoloji Derneği Arşivi, 2017
Objective: We investigated the frequency of different bicuspid aortic valve disease (BAV) phenotypes,the associated valvular pathologies, and the aortopathy phenotypes, using 2-dimensional (2D) transthoracic, 2D transesophageal echocardiography (TEE) and
Selcen Yakar Tülüce, Kamil Tülüce, Ersin Çağrı Şimşek, Özgen Şafak, Mehmet Şefa Ökten, Zeynep Yapan Emren, Sadık Volkan Emren, Uğur Kocabaş, Serdar Bayata, Cem Nazlı   +9 more
doaj   +1 more source

Biomarkers of Aortopathy in Marfan Syndrome [PDF]

Cardiology in Review, 2020
Marfan Syndrome (MFS) is an autosomal dominant, genetically inherited connective tissue disorder which primarily affects the cardiovascular system, but can also have systemic manifestations. First described in 1896, MFS has a prevalence of around 1/5000 in the general population. It is becoming increasingly common to see patients with MFS in a clinical
Iskandar, Zaid, Mordi, Ify, Lang, Chim, Huang, Jeffrey, Choy, Anna   +4 more
openaire   +3 more sources

Novel MYH11 Splice Site Variant Causing Exon Skipping in a Family With Thoracic Aortic Aneurysms and Dissections

Case Reports in Genetics, Volume 2026, Issue 1, 2026.
Background MYH11 variants are associated with thoracic aortic aneurysms and dissections (TAADs) whether or not in combination with patent ductus arteriosus (PDA). MYH11 encodes vascular smooth muscle cell‐specific myosin heavy chain (MHC), and disruptions in this protein are thought to impair cellular function through disturbed intracellular force ...
Aria Atash, Heleen B. van der Zwaan, Maarten J. Cramer, Hans Kirkels, Pieter A. Doevendans, Barend M. E. Mees, Francesca Stillitano, Juliana F. Mazzeu   +7 more
wiley   +1 more source

Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe mechanism underlying aortic dilatation is still unknown. Vascular dilatation is thought to be the result of progressive aortic media degeneration caused by defective vascular matrix hemostasis, including TGF-β1 dysregulation.
Mikita Karalko, Marek Pojar, Lenka Zaloudkova, Vaclav Stejskal, Salifu Timbilla, Pavla Brizova, Jan Vojacek   +6 more
doaj   +1 more source

Cardiovascular genetic counselor decision making about discussing life insurance with patients

Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Genetic counselors (GCs) educate patients about the benefits, risks, and limitations of genetic testing. The regulatory environment governing the use of genetic data in life insurance is not uniform internationally or within the United States (US).
Sara Cherny, Sarah Jurgensmeyer Langas, Miguel Moran, Susan Christian, Gregory Webster   +4 more
wiley   +1 more source