Results 21 to 30 of about 5,408 (223)

Fate of the Aortic Arch Following Surgery on Aortic Root and Ascending Aorta in Bicuspid Aortic Valve. [PDF]

open access: yes, 2018
BACKGROUND: Recent guidelines support more aggressive surgery for aneurysms of the ascending aorta and root in patients with bicuspid aortic valve. However, the fate of the arch after surgery of the root and ascending aorta is unknown.
Bilkhu, R   +11 more
core   +1 more source

Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy

open access: yesFrontiers in Cardiovascular Medicine, 2019
Bicuspid aortic valve (BAV) is the most common congenital cardiac pathology which results from the fusion of two adjacent aortic valve cusps. It is associated with dilatation of the aorta, known as bicuspid valve-associated aortopathy or bicuspid ...
Ali Fatehi Hassanabad   +4 more
doaj   +1 more source

Rationale for the Cytogenomics of Cardiovascular Malformations Consortium: A Phenotype Intensive Registry Based Approach [PDF]

open access: yes, 2015
Cardiovascular malformations (CVMs) are the most common birth defect, occurring in 1%-5% of all live births. Although the genetic contribution to CVMs is well recognized, the genetic causes of human CVMs are identified infrequently.
Bleyl, Steven B.   +8 more
core   +2 more sources

Luetic aortopathy: Revisited

open access: yesIndian Journal of Sexually Transmitted Diseases and AIDS, 2010
We report a case of 38-year-old male, who presented with a large pulsatile swelling on the left side of the anterior chest wall of 4 months' duration with a gradual increase in size. He gave history of sexual promiscuity in the form of unprotected sexual intercourse prior to his marriage in his early 20s. He also gave a history of ulceration on coronal
Madke, Bhushan Sevakram   +5 more
openaire   +3 more sources

Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundMarfan syndrome (MFS) is caused by mutations in the gene encoding fibrillin‐1 (FBN1); however, the mechanisms through which fibrillin‐1 deficiency causes MFS‐associated aortopathy are uncertain. Recently, attention was focused on the hypothesis
Hao Wei   +7 more
doaj   +1 more source

TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]

open access: yes, 2017
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc   +12 more
core   +2 more sources

Bicuspid aortic valve disease:A comprehensive review [PDF]

open access: yes, 2012
Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease.
Mordi, Ify, Tzemos, Nikolaos
core   +4 more sources

Novel Approaches for BAV Aortopathy Prediction—Is There a Need for Cohort Studies and Biomarkers?

open access: yesBiomolecules, 2018
Bicuspid aortic valve (BAV) disease is the most common congenital malformation of the human heart with a prevalence of 1–2% in the general population.
Evaldas Girdauskas   +7 more
doaj   +1 more source

Abnormal wave reflections and left ventricular hypertrophy late after coarctation of the aorta repair [PDF]

open access: yes, 2017
Patients with repaired coarctation of the aorta are thought to have increased afterload due to abnormalities in vessel structure and function. We have developed a novel cardiovascular magnetic resonance protocol that allows assessment of central ...
Khushnood, Abbas   +7 more
core   +2 more sources

A Framework for the Evaluation and Reporting of Outcomes after Complex Heart Valve Interventions: Applications to the European Ross Registry [PDF]

open access: yes, 2014
__Abstract__ Chapter 1 is the general introduction of the thesis. Chapter 2 presents a proposal on the nomenclature of the aortic root components. Chapters 3 and 4 present the single center results with the subcoronary Ross procedure in the University
Charitos, E.I. (Efstratios)
core   +11 more sources

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