Results 11 to 20 of about 5,408 (223)
Aortopathy – A surgical pathology experience
Indian Journal of Pathology and MicrobiologyBackground: Aortopathy is a non-inflammatory and non-atherosclerotic disease of aorta that results from significant ‘degenerative’ changes in the media. This often leads to thoracic aortic aneurysms and/or dissections in young individuals.
Pradeep Vaideeswar, Sujit Udayaravi
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Journal of Cardiothoracic Surgery, 2020 Background Primary and secondary aortopathy are frequently encountered in patients with congenital heart disease. The aim of this study is to present our experience and the incidence of primary and secondary adult CHD-associated aortopathy.
Ingrid Schusterova +4 more
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MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy. [PDF]
PLoS ONE, 2018 MicroRNAs (miRNAs) may serve as elegant tool to improve risk stratification in bicuspid aortic valve (BAV)-associated aortopathy. However, the exact pathogenetic pathway by which miRNAs impact aortopathy progression is unknown.
Evaldas Girdauskas +6 more
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Frontiers in Cardiovascular Medicine, 2023 PurposeCurrent intervention guidelines for bicuspid aortic valve (BAV) associated ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome.
Jiaxing Jason Qin +10 more
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TIMP3 and TIMP1 are risk genes for bicuspid aortic valve and aortopathy in Turner syndrome. [PDF]
PLoS Genetics, 2018 Turner syndrome is caused by complete or partial loss of the second sex chromosome, occurring in ~1 in 2,000 female births. There is a greatly increased incidence of aortopathy of unknown etiology, including bicuspid aortic valve (BAV), thoracic aortic ...
Holly Corbitt +7 more
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JTCVS Open, 2023 Objective: Genetic aortopathy, if left untreated, leads to aortic catastrophe in most affected individuals. We sought to determine the genetic mutation patterns and detection rates in patients with aortopathy and their families with a systematic ...
Jihoon Kim, MD, PhD +6 more
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A Novel Human Biospecimen Repository for Clinical and Molecular Investigation of Thoracic Aortopathy
Cardiogenetics, 2021 Thoracic aortic aneurysm (TAA) is a heritable aortopathy with significant morbidity and mortality, affecting children and adults. Genetic causes, pathobiological mechanisms, and prognostic markers are incompletely understood.
Courtney E. Vujakovich +1 more
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Aortic stenting in the growing sheep causes aortic endothelial dysfunction but not hypertension: Clinical implications for coarctation repair [PDF]
, 2016 Stent implantation is the treatment of choice for adolescents and adults with aortic coarctation (CoAo). Despite excellent short-term results, 20%-40% of the patients develop arterial hypertension later in life, which was attributed to inappropriate ...
Aresu, Luca +14 more
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Frontiers in Cardiovascular Medicine, 2022 Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. Although different molecular players and etiological factors (genetic and hemodynamic) have been suggested ...
María Teresa Soto-Navarrete +21 more
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Open repair of chronic thoracic and thoracoabdominal aortic dissection using deep hypothermia and circulatory arrest [PDF]
, 2017 Background Chronic dissection of the thoracic and thoracoabdominal aorta as sequela of a prior type A or B dissection is a challenging problem that requires close radiographic surveillance and prompt operative intervention in the presence of symptoms ...
Blitzer, David +6 more
core +1 more source