Results 11 to 20 of about 44,747 (260)
Depression and apathy: examining an overlooked dimension [PDF]
Annals of General PsychiatryBackground Apathy is a significant yet frequently overlooked aspect of Major Depressive Disorder (MDD), often confused with anhedonia, and with the potential to influence clinical outcomes and quality of life regardless of the severity of depressive ...
Elvira Anna Carbone +9 more
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Distinct Subtypes of Apathy Revealed by the Apathy Motivation Index. [PDF]
PLoS ONE, 2017 Apathy is a debilitating but poorly understood disorder characterized by a reduction in motivation. As well as being associated with several brain disorders, apathy is also prevalent in varying degrees in healthy people.
Yuen-Siang Ang +4 more
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Apathy and resting state functional connectivity across the Alzheimer's disease continuum [PDF]
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease MonitoringINTRODUCTION This study examined how apathy symptoms and awareness of those symptoms relate to resting‐state functional connectivity magnetic resonance imaging (rs‐fcMRI) across the Alzheimer's disease (AD) continuum using network segregation metrics ...
Gladiliz Rivera‐Delpín +8 more
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Brain Stimulation, 2023 Background: Apathy is reported after subthalamic nucleus deep brain stimulation (STN DBS) and associated with a decreased quality of life in Parkinson's disease (PD) patients.
T.J.C. Zoon +7 more
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A data‐driven examination of apathy and depressive symptoms in dementia with independent replication
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023 Apathy is one of the most common neuropsychiatric symptoms (NPS) and is associated with poor clinical outcomes. Research that helps define the apathy phenotype is urgently needed, particularly for clinical and biomarker studies.
Miguel Vasconcelos Da Silva +6 more
doaj +1 more source
Dimensions of apathy in Parkinson's disease
Brain and Behavior, 2023 Introduction Apathy is one of the most common neuropsychiatric manifestations in Parkinson's disease (PD). Recent proposals consider apathy as a multidimensional construct, which can manifest in behavioral, cognitive, emotional, and/or social dimensions.
Nasya Thompson +4 more
doaj +1 more source
Associations, overlaps and dissociations between apathy and fatigue
Scientific Reports, 2022 Apathy and fatigue have a high prevalence in many pathological populations, but they are also present in healthy adults. The relationship between apathy and fatigue, which are both multidimensional, is still poorly understood. This study aims to describe
Lyne Daumas +6 more
doaj +1 more source
PLoS ONE, 2021 Apathy is defined as reduction of goal-directed behaviors and a common nuisance syndrome of neurodegenerative and psychiatric disease. The underlying mechanism of apathy implicates changes of the front-striatal circuit, but its precise alteration is ...
Chizuko Hamada +5 more
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Identifying and managing apathy in people with dementia living in nursing homes: a qualitative study
BMC Geriatrics, 2023 Background Although apathy is common in people with dementia and has profound negative effects, it is rarely diagnosed nor specifically treated in nursing homes.
Johanna M. H. Nijsten +5 more
doaj +1 more source
Translational Psychiatry, 2021 The purpose of this study is to investigate the complex connection between apathy and cognitive decline that remains unclear. A total of 1057 non-dementia elderly from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database received up to 13 ...
Lin Sun +4 more
doaj +1 more source