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Depression and apathy: examining an overlooked dimension [PDF]
Annals of General PsychiatryBackground Apathy is a significant yet frequently overlooked aspect of Major Depressive Disorder (MDD), often confused with anhedonia, and with the potential to influence clinical outcomes and quality of life regardless of the severity of depressive ...
Elvira Anna Carbone +9 more
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Apathy and impulsivity in frontotemporal lobar degeneration syndromes [PDF]
Brain, 2017 Apathy and impulsivity are common and disabling consequences of frontotemporal lobar degeneration. They cause substantial carer distress, but their aetiology remains elusive.
P Simon Jones +2 more
exaly +5 more sources
Developing a new apathy measurement scale: Dimensional Apathy Scale [PDF]
Psychiatry Research, 2014 Apathy is both a symptom and syndrome prevalent in neurodegenerative disease, including motor system disorders, that affects motivation to display goal directed functions. Levy and Dubois (2006) suggested three apathetic subtypes, Cognitive, Emotional-affective and Auto-activation, all with discrete neural correlates and functional impairments. The aim
Ratko Radakovic, Sharon Abrahams
exaly +5 more sources
Apathy Is Associated with Slower Gait and Subjective Cognitive Complaints in a South Indian Community-Dwelling Cohort [PDF]
Brain SciencesBackground/Objectives: Apathy is an independent risk factor for dementia and motoric–cognitive risk syndrome (MCR), a predementia syndrome characterized by slow gait and subjective cognitive complaints (SCCs).
Matthew G. Engel +8 more
doaj +2 more sources
Brain Stimulation, 2023 Background: Apathy is reported after subthalamic nucleus deep brain stimulation (STN DBS) and associated with a decreased quality of life in Parkinson's disease (PD) patients.
T.J.C. Zoon +7 more
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A data‐driven examination of apathy and depressive symptoms in dementia with independent replication
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023 Apathy is one of the most common neuropsychiatric symptoms (NPS) and is associated with poor clinical outcomes. Research that helps define the apathy phenotype is urgently needed, particularly for clinical and biomarker studies.
Miguel Vasconcelos Da Silva +6 more
doaj +1 more source
Dimensions of apathy in Parkinson's disease
Brain and Behavior, 2023 Introduction Apathy is one of the most common neuropsychiatric manifestations in Parkinson's disease (PD). Recent proposals consider apathy as a multidimensional construct, which can manifest in behavioral, cognitive, emotional, and/or social dimensions.
Nasya Thompson +4 more
doaj +1 more source
Associations, overlaps and dissociations between apathy and fatigue
Scientific Reports, 2022 Apathy and fatigue have a high prevalence in many pathological populations, but they are also present in healthy adults. The relationship between apathy and fatigue, which are both multidimensional, is still poorly understood. This study aims to describe
Lyne Daumas +6 more
doaj +1 more source
PLoS ONE, 2021 Apathy is defined as reduction of goal-directed behaviors and a common nuisance syndrome of neurodegenerative and psychiatric disease. The underlying mechanism of apathy implicates changes of the front-striatal circuit, but its precise alteration is ...
Chizuko Hamada +5 more
doaj +1 more source
Identifying and managing apathy in people with dementia living in nursing homes: a qualitative study
BMC Geriatrics, 2023 Background Although apathy is common in people with dementia and has profound negative effects, it is rarely diagnosed nor specifically treated in nursing homes.
Johanna M. H. Nijsten +5 more
doaj +1 more source