Results 21 to 30 of about 44,747 (260)

Apathy in Parkinson’s Disease: A Retrospective Study of Its Prevalence and Relationship With Mood, Anxiety, and Cognitive Function

Frontiers in Psychology, 2021
Apathy is thought to be an important clinical feature of Parkinson’s disease (PD). However, its prevalence ranges greatly across studies because of differing definitions, assessment tools, and patient inclusion criteria.
Jennifer A. Foley, Jennifer A. Foley, Lisa Cipolotti, Lisa Cipolotti   +3 more
doaj   +1 more source

Apathy and APOE in mild behavioral impairment, and risk for incident dementia

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Introduction Mild behavioral impairment (MBI) is a high‐risk state for incident dementia and comprises five core domains including affective dysregulation, impulse dyscontrol, social inappropriateness, psychotic symptoms, and apathy.
Daniella Vellone, Maryam Ghahremani, Zahra Goodarzi, Nils D. Forkert, Eric E. Smith, Zahinoor Ismail   +5 more
doaj   +1 more source

Distinct Neuropsychological Correlates of Apathy Sub-Domains in Multiple Sclerosis

Brain Sciences, 2023
Background: Apathy is relatively frequent and significantly associated with clinical and cognitive outcomes in Multiple Sclerosis (MS), even if previous research has produced mixed results. This varied picture could be due to most studies treating apathy
Simona Raimo, Mariachiara Gaita, Antonio Costanzo, Daniele Spitaleri, Gabriella Santangelo   +4 more
doaj   +1 more source

Multidimensional apathy in ALS: validation of the Dimensional Apathy Scale [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 2015
Apathy is a prominent symptom of amyotrophic lateral sclerosis (ALS), but measurement is confounded by physical disability. Furthermore, it has been traditionally measured as a unidimensional symptom despite research demonstrating a multifaceted construct.
Radakovic, Ratko, Stephenson, Laura, Colville, Shuna, Swingler, Robert, Chandran, Siddharthan, Abrahams, Sharon   +5 more
openaire   +4 more sources

Apathy is associated with faster global cognitive decline and early nursing home admission in dementia with Lewy bodies

Alzheimer’s Research & Therapy, 2018
Background Little is known about the consequences of apathy in dementia with Lewy bodies (DLB), because previous research on apathy in dementia focused mainly on Alzheimer’s disease (AD).
Monica H. Breitve, Kolbjørn Brønnick, Luiza J. Chwiszczuk, Minna J. Hynninen, Dag Aarsland, Arvid Rongve   +5 more
doaj   +1 more source

Diagnosis and Assessment of Apathy in Elderly Chinese Patients With Cerebral Small Vessel Disease

Frontiers in Psychiatry, 2021
Objective: The study aimed to estimate the frequency of apathy in Chinese patients with cerebral small vessel disease (CSVD) and investigate the relationship between apathy and neuroimaging markers of CSVD.Methods: A total of 150 CSVD aged patients were ...
Hóngyi Zhào, Hóngyi Zhào, Yu Liu, Zhenxi Xia, Hongyang Xie, Yonghua Huang   +5 more
doaj   +1 more source

Detecting apathy in patients with cerebral small vessel disease

Frontiers in Aging Neuroscience, 2022
BackgroundApathy is attracting more and more attention in clinical practice. As one of the most common features of cerebral small vessel disease (CSVD), the assessment of apathy still mainly relies on observers.
Xiaoping Cai, Xiaoping Cai, Hóngyi Zhào, Hóngyi Zhào, Zhiyi Li, Yu Ding, Yonghua Huang   +6 more
doaj   +1 more source

Lower Choline and Myo-Inositol in Temporo-Parietal Cortex Is Associated With Apathy in Amnestic MCI

Frontiers in Aging Neuroscience, 2018
Apathy is a common symptom in patients with amnestic mild cognitive impairment (aMCI) and is associated with an increased risk of progression to Alzheimer’s disease (AD). The neural substrates underlying apathy in aMCI may involve multiple brain regions,
Shankar Tumati, Shankar Tumati, Esther M. Opmeer, Jan-Bernard C. Marsman, Sander Martens, Fransje E. Reesink, Peter P. De Deyn, Peter P. De Deyn, André Aleman, André Aleman   +9 more
doaj   +1 more source

Pain and apathy [PDF]

Dementia & Neuropsychologia, 2008
Abstract In this case report we discuss the lack of emotional reactivity and evasive motor motivation to nociceptive stimuli presented by a patient with frontotemporal degenerative disease and apathy as a predominant behavioral symptom.
openaire   +3 more sources

Apathy and atrophy of subcortical brain structures in Huntington's disease: A two-year follow-up study

NeuroImage: Clinical, 2018
Background: Huntington's disease (HD) is characterized by motor and behavioral symptoms, and cognitive decline. HD gene carriers and their caregivers report the behavioral and cognitive symptoms as the most burdensome.
Verena Baake, Emma M. Coppen, Erik van Duijn, Eve M. Dumas, Simon J.A. van den Bogaard, Rachael I. Scahill, Hans Johnson, Blair Leavitt, Alexandra Durr, Sarah J. Tabrizi, David Craufurd, Raymund A.C. Roos   +11 more
doaj   +1 more source