Results 51 to 60 of about 246,547 (300)

Pain and apathy [PDF]

open access: yesDementia & Neuropsychologia, 2008
Abstract In this case report we discuss the lack of emotional reactivity and evasive motor motivation to nociceptive stimuli presented by a patient with frontotemporal degenerative disease and apathy as a predominant behavioral symptom.
openaire   +5 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Apathy following Bilateral Deep Brain Stimulation of Subthalamic Nucleus and Globus Pallidus Internus in Parkinson’s Disease: A Meta-Analysis

open access: yesParkinson's Disease, 2022
Parkinson’s disease (PD) is a progressive neurodegenerative disorder typically manifested by its motor symptoms. In addition, PD patients also suffer from many nonmotor symptoms (NMSs), such as apathy.
Song Zhang   +5 more
doaj   +1 more source

Rest-activity disturbances and light exposure in myotonic dystrophy type 1 patients with apathy: An exploratory study using actigraphy

open access: yesJournal of Affective Disorders Reports, 2023
Background: Rest-activity rhythm disturbances have been reported in myotonic dystrophy type 1 (DM1) but no study has assessed its relationship with apathy and light exposure using actigraphy.
Luc Laberge   +5 more
doaj   +1 more source

Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy. [PDF]

open access: yes, 2016
OBJECTIVE: To study the stability and emergence of a range of behavioural and psychological symptoms (BPS), their association with mortality and the effect of covariates on these transitions in a population-based study of cognitively impaired older ...
Brayne, Carol   +3 more
core   +3 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Kant's apathology of compassion [PDF]

open access: yes, 2014
In his critical and his later work, Kant recommends apathy to the moral agent faced with pathological phenomena. Notoriously, Kant even rejects compassion (Mitleiden) as pathological. A deconstruction of Kant's 'apathology', i.e.
Bergande, Wolfram
core  

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Fascism as a Mass-Movement: Translator's Introduction [PDF]

open access: yes, 2012
This Introduction to Rosenberg’s essay starts with a brief synopsis of his life, then summarises the key arguments of the essay itself before looking briefly at the twin issues of the social base of the fascist parties (wider than just the ‘petty ...
Banaji, Jairus
core   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

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