Results 111 to 120 of about 531,671 (288)

Global OA APCs (APC) 2010-2017: Major Trends

open access: yes22nd International Conference on Electronic Publishing, 2018
The open access (OA) article processing charges (APC) project is a longitudinal study of the minority of fully OA journals (27% in 2016) that have APCs. The global average APC shows little change; in USD, 906 in 2010, 964 in 2016, 974 in 2017. The average masks currency differences and the impact of a growing market; new APC journals often start with ...
openaire   +4 more sources

GSH‐Responsive Nanoparticles Enhance Hepatocellular Carcinoma Immunotherapy Through Synergistic Effects of Cuproptosis and PI3K Inhibitor Combination

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cuproptosis, an emerging form of programmed cell death, is capable of inducing mitochondrial dysfunction. Moreover, the PI3K‐AKT‐mTOR signaling pathway contributes to tumor cell progression by reprogramming mitochondrial morphology and function.
Lei Wu   +10 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

APC Autocare

open access: yes, 2022
APC Auto Care provide enthusiast level care for car lovers throughout Melbourne. We've translated our passion for cars into a premium car care service, allowing us to deliver exceptional results for our clients. Our services cover every aspect of aesthetic car cleaning and protection, including interior and exterior washing and detailing, steam ...
openaire   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

open access: yesAdvanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu   +16 more
wiley   +1 more source

Know your APC

open access: yesBlood, 2009
Ala scanning mutagenesis of the activation peptide singles out E149A, a mutant activated protein C (APC) that exhibits enhanced anticoagulant activity but greatly diminished cytoprotective effects compared with wild-type. Notwithstanding its enhanced antithrombotic activity in vivo, the variant APC is poorly effective in reducing endotoxin-induced ...
openaire   +3 more sources

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Open Access needs terminology to distinguish between Gold OA funding models [PDF]

open access: yes, 2012
Shedding further light on the wider open access debate, Martin Eve calls for a more precise terminology for the variety of Gold OA business models that currently exist to help correct the false assumption in many academics’ minds that Gold OA necessarily
Eve, Martin
core  

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

APC [PDF]

open access: yesCurrent Biology, 2003
openaire   +2 more sources

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