Results 81 to 90 of about 158,301 (286)

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

Advanced Science, EarlyView.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu, Xianlan Chen, Jin Wang, Yuhan Liu, Sidra Mustafa, Lu Diao, Rongrong Zhao, Haiyang Chi, Kang Hu, Jiashan Zhu, Jun Zhao, Mi Liu   +11 more
wiley   +1 more source

Integrating a QPSK Quantum Key Distribution Link [PDF]

, 2006
We present the integration of the optical and electronic subsystems of a BB84-QKD fiber link. A highspeed FPGA MODEM generates the random QPSK sequences for a fiber-optic delayed self-homodyne scheme using APD detectors.Comment: 2 pages, 4 figures ...
Agnolini, S., Danger, J-L., Gallion, P., Guilley, S., Mendieta, F. J., Silva, M. B. Costa e, Xu, Q.   +6 more
core   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Factors Influencing the Choice of Automated Peritoneal Dialysis Treatment by Patients Receiving Home Peritoneal Dialysis

Patient Preference and Adherence, 2023
Fang Cao,1,2 Fuyuan Hong,1 Yiping Ruan,1 Miao Lin1 1Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, Fuzhou, 350001, People’s Republic of China; 2Department of Nursing, Provincial Clinical ...
Cao F, Hong F, Ruan Y, Lin M
doaj  

Performance of various quantum key distribution systems using 1.55 um up-conversion single-photon detectors

, 2005
We compare the performance of various quantum key distribution (QKD) systems using a novel single-photon detector, which combines frequency up-conversion in a periodically poled lithium niobate (PPLN) waveguide and a silicon avalanche photodiode (APD ...
A. V. Vandevender, C. H. Bennett, D. S. Bethune, Eleni Diamanti, G. Brassard, Hiroki Takesue, Kyo Inoue, M. Bourennane, M. Koashi, S. Fasel, Toshimori Honjo, Yoshihisa Yamamoto   +11 more
core   +1 more source

A numerical investigation into the correction algorithms for SPH method in modeling violent free surface flows [PDF]

, 2014
A quantitative comparison of the usual and recent numerical treatments which are applied to the Smoothed Particle Hydrodynamics (SPH) method are presented together with a new free-surface treatment.
Gören, Ömer, Yıldız, Mehmet, Özbulut, Murat   +2 more
core   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Geometry and Physics on $w_{\infty}$ Orbits

, 1993
We apply the coadjoint orbit technique to the group of area preserving diffeomorphisms (APD) of a 2D manifold, particularly to the APD of the semi-infinite cylinder which is identified with $w_{\infty}$.
Selivanov, K. G.
core   +2 more sources

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy. [PDF]

, 2020
Intraperitoneal vancomycin is the first-line therapy in the management of peritoneal dialysis (PD)-related peritonitis. However, due to the paucity of data, vancomycin dosing for peritonitis in patients on automated peritoneal dialysis (APD) is empiric ...
Kraft, Walter K., Lam, Edwin, Lien, Yi Ting Kayla, Piraino, Beth, Schmidt, Stephan, Vozmediano, Valvanera, Zhang, Jingjing   +6 more
core   +1 more source