Specific inhibition of aphthovirus infection by RNAs transcribed from both the 5' and the 3' noncoding regions [PDF]
RNA molecules containing the 3' terminal region of foot-and-mouth disease virus (FMDV) RNA in both antisense and sense orientations were able to inhibit viral FMDV translation and infective particle formation in BHK-21 cells following comicroinjection or cotransfection with infectious viral RNA.
Alfonso Gutiérrez‐Adán +3 more
openalex +5 more sources
An analysis of published nucleotide sequences of the 5'-untranslated region (5'-UTR) of 7 cardioviruses and 3 aphthoviruses has allowed us to derive a consensus secondary structure model that differs from that previously proposed for the 5'-UTR of entero- and rhinoviruses, though all these viruses belong to the same family, Picornaviridae.
Evgeny V. Pilipenko +4 more
openalex +5 more sources
Movement Networks of Domestic Livestock Susceptible to Food and Mouth Disease in Thailand. [PDF]
Foot and mouth disease (FMD) is one of the most common diseases in livestock that causes great losses to industrial livestock production. FMD may spread through animal movements. Therefore, this study aimed to analyze the patterns of domestic livestock movements susceptible to FMD using social network analysis and exponential random graph models (ERGMs)
Thongratsakul S +2 more
europepmc +2 more sources
Oral and Faecal Viromes of New Zealand Calves on Pasture With an Idiopathic Ill-Thrift Syndrome. [PDF]
Since 2015, an idiopathic ill‐thrift syndrome featuring diarrhoea and, in some cases, gastrointestinal ulceration has been reported in weaned New Zealand dairy calves. Similar syndromes have been described in the British Isles and Australia, but investigations in New Zealand have yet to identify a specific cause. Notably, the viromes of affected calves
Grimwood RM +8 more
europepmc +2 more sources
Cell Recognition by Foot-and-Mouth Disease Virus That Lacks the RGD Integrin-Binding Motif: Flexibility in Aphthovirus Receptor Usage [PDF]
ABSTRACT Cell surface molecules that can act as virus receptors may exert an important selective pressure on RNA viral quasispecies. Large population passages of foot-and-mouth disease virus (FMDV) in cell culture select for mutant viruses that render dispensable a highly conserved Arg-Gly-Asp (RGD) motif responsible for integrin
Éric Baranowski +5 more
openalex +5 more sources
Serotype Diversity and Molecular Characterization of Foot-and-Mouth Disease Viruses From Outbreaks in Ethiopia (2019-2023): Re-Emergence of SAT 2 After 30 Years. [PDF]
Ethiopia faces significant economic losses from foot‐and‐mouth disease (FMD). Laboratory diagnostic tools such as antigen detection ELISA (Ag‐ELISA), reverse transcription polymerase chain reaction (RT‐PCR), and sequencing provide important information that underpin control initiatives.
Gizaw D +14 more
europepmc +2 more sources
Cell Entry of the Aphthovirus Equine Rhinitis A Virus Is Dependent on Endosome Acidification [PDF]
ABSTRACT Equine rhinitis A virus (ERAV) is genetically closely related to foot-and-mouth disease virus (FMDV), and both are now classified within the genus Aphthovirus of the family Picornaviridae .
Elisabetta Groppelli +2 more
openalex +3 more sources
The strategies developed by internal ribosome entry site (IRES) elements to recruit the translational machinery are poorly understood. In this study we show that protein-RNA interaction of the eIF4G translation initiation factor with sequences of the foot-and-mouth disease virus (FMDV) IRES is a key determinant of internal translation initiation in ...
Sonia López de Quinto +1 more
openalex +4 more sources
Statistical analyses of RNA folding in 5' nontranslated regions (5'NTR) of encephalomyocarditis virus, Theiler's murine encephalomyelitis virus, foot-and-mouth disease virus, and hepatitis A virus indicate that two highly significant folding regions occur in the 5' and 3' portions of the 5'NTR.
Shu‐Yun Le +3 more
openalex +5 more sources
Phylogenetic Characterization and Pathogenicity in Cattle and Pigs of Foot-and-Mouth Disease Viruses Circulating in Myanmar Between 2016 and 2022. [PDF]
Foot‐and‐mouth disease (FMD) is a highly contagious and serious transboundary disease affecting cloven‐hoofed animals. Myanmar is a critical area for FMD outbreaks in Southeast and East Asian regions because of its geographical location bordering South Asian countries and its cattle industry.
Kawaguchi R +4 more
europepmc +2 more sources

