Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes. [PDF]
PLoS Pathogens, 2017 Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the ...
Elisabetta Groppelli +9 more
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Four Independent Antigenic Determinants on the Capsid Polypeptides of Aphthovirus
Journal of General Virology, 1983 Four independent antigenic determinants in the virus capsid have been defined in radioimmunoassay tests using antisera prepared against isolated structural polypeptides VP1, 2 and 3. Only one determinant was detected on the intact particle and it was contained within VP1 (called the VP1-A determinant).
Haresnape, Janet M., McCahon, David
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Equine Rhinitis A Virus Mutants with Altered Acid Resistance Unveil a Key Role of VP3 and Intrasubunit Interactions in the Control of the pH Stability of the Aphthovirus Capsid [PDF]
Journal of Virology, 2016 Flavia Caridi +4 more
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Putative papain‐related thiol proteases of positive‐strand RNA viruses Identification of rubi‐ and aphthovirus proteases and delineation of a novel conserved domain associated with proteases of rubi‐, α‐ and coronaviruses [PDF]
FEBS Letters, 1991 Alexander E. Gorbalenya +2 more
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Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]
, 2014 Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony +10 more
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Foot-and-Mouth Disease Virus Interserotypic Recombination in Superinfected Carrier Cattle
Pathogens, 2022 Viral recombination contributes to the emergence of novel strains with the potential for altered host range, transmissibility, virulence, and immune evasion.
Ian Fish +10 more
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The long-lasting enigma of polycytidine (polyC) tract
PLoS Pathogens, 2021 Long polycytidine (polyC) tracts varying in length from 50 to 400 nucleotides were first described in the 5′-noncoding region (NCR) of genomes of picornaviruses belonging to the Cardio- and Aphthovirus genera over 50 years ago, but the molecular basis of
Velia Penza +2 more
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Detection of Clinical and Subclinical Foot and Mouth Disease Virus in Cattle in Al-Najaf Province [PDF]
Archives of Razi Institute, 2022 Foot-and-mouth disease (FMD) is a highly transmissible disease caused by Aphthovirus of the family Picornaviridae. This study aimed to investigate the serological approach (non-structural protein [NSP] analysis) of 3ABC enzyme-linked immunosorbent assay (
A Abd Hatem +3 more
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Pathogens, 2020 Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish +4 more
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