The long-lasting enigma of polycytidine (polyC) tract
Long polycytidine (polyC) tracts varying in length from 50 to 400 nucleotides were first described in the 5′-noncoding region (NCR) of genomes of picornaviruses belonging to the Cardio- and Aphthovirus genera over 50 years ago, but the molecular basis of
Velia Penza +2 more
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Identification of an essential region for internal initiation of translation in the aphthovirus internal ribosome entry site and implications for viral evolution [PDF]
Translation of aphthovirus RNA is initiated at an internal ribosome entry site (IRES) element, preceding the first functional AUG initiation codon. The effect of mutations at the base of domain 3 of the aphthovirus IRES on translation activity has been analyzed by site-directed mutagenesis and expression of bicistronic RNAs in transfected cells.
Encarnación Martı́nez-Salas +2 more
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Heterogeneity of the polyribocytidylic acid tract in aphthovirus: biochemical and biological studies of viruses carrying polyribocytidylic acid tracts of different lengths [PDF]
In this paper we report a study of a sample of foot-and-mouth disease virus carrying two polyribocytidylic acid [poly(C)] tracts of different lengths. By plaque purification in tissue culture, we isolated two populations of particles, one carrying the long poly(C) tract and the other carrying only the short homopolymer. The fingerprints of both viruses
M.P. Costa Giomi +5 more
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Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected
Ian Fish +4 more
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Detection of Clinical and Subclinical Foot and Mouth Disease Virus in Cattle in Al-Najaf Province [PDF]
Foot-and-mouth disease (FMD) is a highly transmissible disease caused by Aphthovirus of the family Picornaviridae. This study aimed to investigate the serological approach (non-structural protein [NSP] analysis) of 3ABC enzyme-linked immunosorbent assay (
A Abd Hatem +3 more
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Mapping the likelihood of foot-and-mouth disease introduction along the border between Brazil and Paraguay [PDF]
: The objective of this work was to apply fuzzy majority multicriteria group decision-making to determine risk areas for foot-and-mouth disease (FMD) introduction along the border between Brazil and Paraguay.
Thaís Basso Amaral +2 more
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Serum biochemical and oxidative status in Holstein cattle affected with foot and mouth disease [PDF]
Foot and mouth disease (FMD) is a severe, highly contagious viral disease of cloven-hoofed ruminants caused by an aphthovirus of the family Picornaviridae.
Hosseinali Soltani +3 more
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Expression and stability of foreign epitopes introduced into 3A nonstructural protein of foot-and-mouth disease virus. [PDF]
Foot-and-mouth disease virus (FMDV) is an aphthovirus that belongs to the Picornaviridae family and causes one of the most important animal diseases worldwide. The capacity of other picornaviruses to express foreign antigens has been extensively reported,
Pinghua Li +7 more
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Foot and Mouth Disease (FMD) was first reported in 1987 in Malang, East Java, caused by imported dairy cattle from the Netherlands. After 36 years of FMD freedom, the disease was re-introduced on 5 May 2022 in East Java.
Hendro Sukoco +5 more
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Foot-and-Mouth Disease in the Middle East Caused by an A/ASIA/G-VII Virus Lineage, 2015–2016
Phylogenetic analyses of foot-and-mouth disease type A viruses in the Middle East during 2015–2016 identified viruses belonging to the A/ASIA/G-VII lineage, which originated in the Indian subcontinent.
Katarzyna Bachanek-Bankowska +12 more
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