Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe
RNA viruses replicate as complex distributions of non-identical but closely related variant genomes termed viral quasispecies. When the error rate during genome replication exceeds a threshold value, the genetic information cannot be maintained and the system enters error catastrophe.
González-López, Claudia +3 more
openaire +3 more sources
RNA-protein interaction methods to study viral IRES elements [PDF]
Translation control often takes place through the mRNA untranslated regions, involving direct interactions with RNA-binding proteins (RBPs). Internal ribosome entry site elements (IRESs) are cis-acting RNA regions that promote translation initiation ...
Díaz-Toledano, Rosa +4 more
core +1 more source
Structures and Corresponding Functions of Five Types of Picornaviral 2A Proteins
Among the few non-structural proteins encoded by the picornaviral genome, the 2A protein is particularly special, irrespective of structure or function. During the evolution of the Picornaviridae family, the 2A protein has been highly non-conserved.
Xiaoyao Yang +34 more
doaj +1 more source
Employing transposon mutagenesis to investigate foot-and-mouth disease virus replication [PDF]
Probing the molecular interactions within the foot-and-mouth disease virus (FMDV) RNA replication complex has been restricted in part to the lack of suitable reagents.
Belsham +17 more
core +1 more source
Foot-and-mouth disease (FMD) is a highly contagious viral disease, which has been reported for over 100 years, and against which the struggle has lasted for the same amount of time.
Ibett Rodríguez-Habibe +4 more
doaj +1 more source
Application of commercial enzyme linked immunosorbent assays (ELISA) for the detection of antibodies for foot-and-mouth disease virus in wild boar and red deer [PDF]
For detecting antibodies towards foot and mouth (FMD) virus in sera collected from red deer hinds (Cervus elaphus) and wild boars (Sus scrofa), three commercially available enzyme-linked immunosorbent assays (ELISA) were used.
Florijančić T. +3 more
core +1 more source
Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley +1 more source
Phylogenic analysis of serotype Asia1 foot-and-mouth disease virus from Sulaimani/Iraq using VP1 protein: heterogeneity with vaccine strain As1/Shamir/89 [PDF]
Foot-and-mouth disease virus (FMDV) serotypes O, A and Asia1 are responsible for a significant number of disease outbreaks in Iraq. The current study can be considered as the first molecular characterization of serotype Asia1 in Iraq.
Baba Sheikh, Mohammed O. +4 more
core +1 more source
An N‐glycosylation was strategically introduced at the 166th position of VP1 via artificial mutagenesis. The glycans mainly consist of high‐mannose type, significantly enhancing the stability and uptake of VLPs. The glycosylated VLPs conferred a robust Th1‐type immune response in mice and pigs and provided 100% protection against FMDV in pigs ...
Zhiyao Li +10 more
wiley +1 more source
Developing Vaccines Against Foot-and-Mouth Disease: A Biotechnological Approach [PDF]
Foot-and-mouth disease (FMD) is a contagious viral disease of livestock with significant economic effect. It is prevalent in various regions of Asia, Africa, and South America.
A. Shahriari, M. Habibi-Pirkoohi
doaj +1 more source

