Regulation of apical constriction via microtubule- and Rab11-dependent apical transport during tissue invagination. [PDF]
Mol Biol Cell, 2021 During tissue invagination, contractile actomyosin structures generate the cellular forces that drive apical constriction. Using the Drosophila embryonic salivary gland as a model for epithelial tube formation, we show that microtubule- and Rab11-dependent apical transport is critical for regulating actomyosin networks during invagination.
Le TP, Chung S.
europepmc +6 more sources
Morphotypes of the apical constriction of maxillary molars: a micro-computed tomographic evaluation [PDF]
Restorative Dentistry & Endodontics, 2022 ObjectivesThe aim of this study was to evaluate and compare the apical constriction (AC) and apical canal morphology of maxillary first and second molars, using micro-computed tomography (micro-CT).Materials and MethodsThe anatomical features of 313 root
Jeffrey Wen-Wei Chang +6 more
doaj +3 more sources
Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction [PDF]
Biology Open, 2016 Early development of the gut endoderm and its subsequent remodeling for the formation of organ buds are accompanied by changes to epithelial cell shape and polarity.
David A. F. Loebel +5 more
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Apical constriction: A cell shape change that can drive morphogenesis [PDF]
Developmental Biology, 2010 Biologists have long recognized that dramatic bending of a cell sheet may be driven by even modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like these are at the core of many of the morphogenetic movements that shape animal form during development, driving processes such as gastrulation, tube formation and ...
Bob Goldstein, Minna Roh-Johnson
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Apical constriction: themes and variations on a cellular mechanism driving morphogenesis. [PDF]
Development, 2014 Apical constriction is a cell shape change that promotes tissue remodeling in a variety of homeostatic and developmental contexts, including gastrulation in many organisms and neural tube formation in vertebrates. In recent years, progress has been made towards understanding how the distinct cell biological processes that together drive apical ...
Martin AC, Goldstein B.
europepmc +5 more sources
Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry [PDF]
Developmental Biology, 2023 Neuroepithelial cells balance tissue growth requirement with the morphogenetic imperative of closing the neural tube. They apically constrict to generate mechanical forces which elevate the neural folds, but are thought to apically dilate during mitosis.
Gabriel Galea
exaly +6 more sources
Actomyosin contractility and microtubules drive apical constriction in Xenopus bottle cells [PDF]
Developmental Biology, 2007 Cell shape changes are critical for morphogenetic events such as gastrulation, neurulation, and organogenesis. However, the cell biology driving cell shape changes is poorly understood, especially in vertebrates. The beginning of Xenopus laevis gastrulation is marked by the apical constriction of bottle cells in the dorsal marginal zone, which bends ...
Lee, Jen-Yi, Harland, Richard M.
exaly +4 more sources
Lulu regulates Shroom-induced apical constriction during neural tube closure. [PDF]
PLoS ONE, 2013 Apical constriction is an essential cell behavior during neural tube closure, but its underlying mechanisms are not fully understood. Lulu, or EPB4.1l5, is a FERM domain protein that has been implicated in apical constriction and actomyosin contractility
Chih-Wen Chu +3 more
doaj +2 more sources
Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts [PDF]
Development, 2017 Cell delamination is a conserved morphogenetic process important for generation of cell diversity and maintenance of tissue homeostasis. Here we used Drosophila embryonic neuroblasts as a model to study the apical constriction process during cell delamination.
Yanru An +8 more
core +6 more sources
Evaluation and Comparison of the Position of the Apical Constriction in Single-root and Multiple-root Teeth [PDF]
Journal of Mashhad Dental School, 2017 Introduction: Precise knowledge of the location of the apical constriction is essential to root canal treatment and long-term prognosis. Considering the differences in the apical constriction and size of the roots in single- and multiple-root teeth in ...
Alireza Farhad +4 more
doaj +2 more sources