Results 1 to 10 of about 12,721 (106)

The flexibility of Apicomplexa parasites in lipid metabolism

open access: yesPLoS Pathogens, 2022
Apicomplexa are obligate intracellular parasites responsible for major human infectious diseases such as toxoplasmosis and malaria, which pose social and economic burdens around the world. To survive and propagate, these parasites need to acquire a significant number of essential biomolecules from their hosts. Among these biomolecules, lipids are a key
Serena Shunmugam   +2 more
exaly   +6 more sources

Versatility in the acquisition of energy and carbon sources by the Apicomplexa [PDF]

open access: yesBiology of the Cell, 2010
Members of the phylum Apicomplexa are motile and rapidly dividing intracellular parasites, able to occupy a large spectrum of niches by infecting diverse hosts and invading various cell types. As obligate intracellular parasites, most apicomplexans only survive for a short period extracellularly, and, during this time, have a high energy demand to ...
Valérie Polonais   +1 more
exaly   +7 more sources

Essential Genes of the Parasitic Apicomplexa [PDF]

open access: yesTrends in Parasitology, 2021
Genome-scale mutagenesis screens for genes essential for apicomplexan parasite survival have been completed in three species: Plasmodium falciparum, the major human malaria parasite, Plasmodium berghei, a model rodent malaria parasite, and the more distantly related Toxoplasma gondii, the causative agent of toxoplasmosis. These three species share 2606
Oberstaller, Jenna   +3 more
openaire   +3 more sources

Mobilome of Apicomplexa Parasites

open access: yesGenes, 2022
Transposable elements (TEs) are mobile genetic elements found in the majority of eukaryotic genomes. Genomic studies of protozoan parasites from the phylum Apicomplexa have only reported a handful of TEs in some species and a complete absence in others.
Matias Rodriguez, Wojciech Makalowski
openaire   +4 more sources

The Actomyosin Systems in Apicomplexa [PDF]

open access: yes, 2020
The phylum of Apicomplexa groups obligate intracellular parasites that exhibit unique classes of unconventional myosin motors. These parasites also encode a limited repertoire of actins, actin-like proteins, actin-binding proteins and nucleators of filamentous actin (F-actin) that display atypical properties.
Frénal, Karine   +2 more
openaire   +4 more sources

Extrachromosomal DNA in the Apicomplexa. [PDF]

open access: yesMicrobiology and molecular biology reviews : MMBR, 1997
Malaria and related apicomplexan parasites have two highly conserved organellar genomes: one is of plastid (pl) origin, and the other is mitochondrial (mt). The organization of both organellar DNA molecules from the human malaria parasite Plasmodium falciparum has been determined, and they have been shown to be tightly packed with genes.
R. J. M. Wilson, D. H. Williamson
openaire   +3 more sources

Cryptosporidium rubeyi n. sp. (Apicomplexa: Cryptosporidiidae) in multiple Spermophilus ground squirrel species. [PDF]

open access: yes, 2015
Previously we reported the unique Cryptosporidium sp. "c" genotype (e.g., Sbey03c, Sbey05c, Sbld05c, Sltl05c) from three species of Spermophilus ground squirrel (Spermophilus beecheyi, Spermophilus beldingi, Spermophilus lateralis) located throughout ...
Atwill, Edward R   +7 more
core   +7 more sources

Divergent polyamine metabolism in the Apicomplexa [PDF]

open access: yesMicrobiology, 2007
The lead enzymes of polyamine biosynthesis, i.e. ornithine decarboxylase (ODC) and arginine decarboxylase (ADC), were not detected in Toxoplasma gondii [the limit of detection for ODC and ADC was 5 pmol min(-1) (mg protein)(-1)], indicating that T. gondii lacks a forward-directed polyamine biosynthetic pathway, and is therefore a polyamine auxotroph ...
David S. Roos   +7 more
openaire   +3 more sources

Coccidia (Apicomplexa: Eimeriidae) of Three-toed Box Turtles, Terrapene carolina triunguis (Reptilia: Testudines), from Arkansas and Oklahoma [PDF]

open access: yes, 2015
We collected 50 three-toed box turtles (Terrapene carolina triunguis) from 9 counties of Arkansas and 4 counties of Oklahoma, and examined their feces for coccidial parasites.
Connior, M. B.   +5 more
core   +3 more sources

Upscaling the surveillance of tick-borne pathogens in the French Caribbean Islands [PDF]

open access: yes, 2020
Despite the high burden of vector-borne disease in (sub)tropical areas, few information are available regarding the diversity of tick and tick-borne pathogens circulating in the Caribbean.
Albina, Emmanuel   +9 more
core   +1 more source

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