Results 141 to 150 of about 16,726 (193)

Applications and prospects of cryo-electron tomography in drug discovery and understanding disease. [PDF]

Curr Opin Struct Biol
Clemente CM, Mobarec JC, Bharat TAM.
europepmc   +1 more source

Decoding the Minimal Translation System of the Plasmodium falciparum Apicoplast: Essential tRNA-modifying Enzymes and Their Roles in Organelle Maintenance. [PDF]

J Mol Biol
Elahi R, Mesones Mancilla S, Sievert ML, Ribeiro Dinis L, Adewale-Fasoro O, Mann A, Zur Y, Prigge ST.   +7 more
europepmc   +1 more source

The Putative E3 Ubiquitin Ligase TEX1 Is Required for Nuclear Biology and Developmental Progression of <i>Plasmodium berghei</i> in the Liver. [PDF]

Cells
Schmid M, Golomingi R, Franke-Fayard B, Caldelari R, Rehmann R, Roques M, Heussler VT.   +6 more
europepmc   +1 more source

Toxoplasma gondii SIR2A Promotes Tachyzoite Invasion via Lysine Deacetylase Activity. [PDF]

FASEB J
Wu Y, Liu X, Tian X, Xie Y, Wu Y, Zheng X, Hu X, Hua Q, Zhao W, Mou Y, Tan F.   +10 more
europepmc   +1 more source

Genome sequence of <i>Babesia gibsoni</i> detected in a domestic dog in New Zealand. [PDF]

Microbiol Resour Announc
Wilson A, Jauregui R, Bueno R, Begg D, Hannah M, Sheeba E, Bestbier M, Green D, O'Keefe J, McCulley M.   +9 more
europepmc   +1 more source

Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum. [PDF]

Nucleic Acids Res
Kumari A, Enache T, Craggs TD, Pata JD, Lahiri I.   +4 more
europepmc   +1 more source

The spatial proteome of the Plasmodium falciparum schizont illuminates the composition and evolutionary trajectories of its organelles

Chisholm SA, Flores V, Kemp A, Breckels LM, Koreny L, Santos Pacheco ND, Barylyuk K, Kuroshchenkova A, Lilley KS, Rayner JC, Waller RF.   +10 more
europepmc   +1 more source

Exploiting the apicoplast: apicoplast-targeting drugs and malaria vaccine development [PDF]

Microbes and Infection, 2018
The apicoplast, a relic plastid found in most Apicomplexan parasites, is a notable drug target. Certain antibiotics elicit a delayed death phenotype by targeting this organelle. Here, we review apicoplast-targeting drugs and their targets, particularly those that cause delayed death, and highlight its potential uses in malaria vaccine development.
Michael Good, Leanne M Low, Danielle Stanisic   +2 more
exaly   +6 more sources

The evolution, metabolism and functions of the apicoplast [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2010
The malaria parasite, Plasmodium falciparum , harbours a relict plastid known as the ‘apicoplast’. The discovery of the apicoplast ushered in an exciting new prospect for drug development against the parasite.
Geoff McFadden
exaly   +6 more sources