Results 51 to 60 of about 17,169 (224)
Annotation and characterization of Babesia gibsoni apicoplast genome
Parasites & Vectors, 2020 Background Babesia gibsoni is an apicomplexan parasite transmitted by ticks, which can infect canine species and cause babesiosis. The apicoplast is an organelle associated with isoprenoids metabolism, is widely present in apicomplexan parasites, except ...
Qin Liu +9 more
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mBio, 2018 Plasmodium parasites and related pathogens contain an essential nonphotosynthetic plastid organelle, the apicoplast, derived from secondary endosymbiosis.
Marta Walczak +3 more
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The interdependence of isoprenoid synthesis and apicoplast biogenesis in malaria parasites.
PLoS Pathogens, 2023 Isoprenoid precursor synthesis is an ancient and fundamental function of plastid organelles and a critical metabolic activity of the apicoplast in Plasmodium malaria parasites [1-3].
Megan Okada, Paul A Sigala
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The apicoplast is important for the viability and persistence of Toxoplasma gondii bradyzoites
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance In its intermediate hosts, the parasite Toxoplasma gondii can persist as a cyst-contained developmental form that might reactivate and cause severe pathologies. Importantly, this form is resistant to current antiparasitic drugs. T.
Syrian G. Sanchez +6 more
semanticscholar +2 more sources
mBio, 2020 Plasmodium parasites and related apicomplexans contain an essential “complex plastid” organelle of secondary endosymbiotic origin, the apicoplast. Biogenesis of this complex plastid poses a unique challenge requiring evolution of new cellular machinery ...
Thomas R. Meister +3 more
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A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites.
PLoS Pathogens, 2020 Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium.
Russell P Swift +11 more
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mBio, 2017 Apicomplexan parasites cause a variety of important infectious diseases, including malaria, toxoplasma encephalitis, and severe diarrhea due to Cryptosporidium.
Justin D. Fellows +3 more
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Theileria Apicoplast as a Target for Chemotherapy [PDF]
Antimicrobial Agents and Chemotherapy, 2009 ABSTRACT Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets.
Regina, Lizundia +3 more
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The suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasites. [PDF]
PLoS Pathogens, 2013 The apicoplast organelle of the malaria parasite Plasmodium falciparum contains metabolic pathways critical for liver-stage and blood-stage development.
Jolyn E Gisselberg +4 more
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Genetic characterization of Plasmodium berghei apicoplast proteins [PDF]
, 2013 Malaria wird durch den einzelligen Parasiten Plasmodium verursacht. Hierbei handelt es sich um einen obligat intrazellulären, eukaryotischen Erreger, der zum Phylum der Apicomplexa gehört.
Haußig, Joana
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