Results 61 to 70 of about 17,169 (224)

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host

, 2005
The structure and location of Toxoplasma gondii apicoplasts were examined in intermediate and definitive hosts and shown to vary in a stage-specific manner.
Henriquez, F L, Muench, S P, Kirisits, M J, Rice, DW, Prigge, ST, Henriquez, FL, Ferguson, DJ, Ferguson, D J P, Rice, D W, Roberts, C W, McLeod, R L, McLeod, RL, Ferguson, David, Kirisits, MJ, Prigge, S T, Muench, SP, Roberts, CW   +16 more
core   +1 more source

Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling

Cell Reports, 2020
Summary: Apicomplexan parasites are unicellular eukaryotic pathogens that must obtain and combine lipids from both host cell scavenging and de novo synthesis to maintain parasite propagation and survival within their human host.
Souad Amiar, Nicholas J. Katris, Laurence Berry, Sheena Dass, Samuel Duley, Christophe-Sebastien Arnold, Melanie J. Shears, Camille Brunet, Bastien Touquet, Geoffrey I. McFadden, Yoshiki Yamaryo-Botté, Cyrille Y. Botté   +11 more
doaj   +1 more source

pr2‐Wormifier: A Bioinformatics Pipeline to Create Custom Reference Databases for Improved Metabarcoding of Marine Protists

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Metabarcoding of environmental and ancient environmental DNA (eDNA and sedaDNA) is a powerful approach for studying and monitoring marine communities. However, its effectiveness is limited by the availability of comprehensive and well‐curated reference databases, particularly for protists.
Stefanie Knell, Juliane Romahn, Miklós Bálint   +2 more
wiley   +1 more source

Phytochemical Diversity, Nutritional Values, and Biological Properties of Halopithys incurva (Hudson) Batters, 1902

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Youssra Aalilou, Abdelhakim Bouyahya, Kaoutar Benrahou, Mustapha Hassoun, Hanaa Moussa, Issam Ameziane El Hassani, Waleed Al Abdulmonem, Learn‐Han Lee, Gokhan Zengin, My El Abbes Faouzi   +9 more
wiley   +1 more source

GFP-targeting allows visualization of the apicoplast throughout the life cycle of live malaria parasites.

, 2009
BACKGROUND INFORMATION The Plasmodium parasite, during its life cycle, undergoes three phases of asexual reproduction, these being repeated rounds of erythrocytic schizogony, sporogony within oocysts on the mosquito midgut wall and exo-erythrocytic ...
Zobiak, Bernd, Aepfelbacher, Martin, Stanway, Rebecca R, Witt, Tina, Heussler, Volker   +4 more
core   +1 more source

Transcriptomic analysis of apicoplast-disrupted parasites.

, 2020
A) Hierarchical clustering of apicoplast genome expression from control and apicoplast-disrupted parasites during the IDC. The apicoplast gene expression data were normalized by the median expression of 5851 genes from corresponding parasites at each ...
Hans B. Liu (8452467), Anders Wallqvist (43485), Shivendra G. Tewari (8452482), Amanda Dziedzic (2549350), Russell P. Swift (8452464), Sean T. Prigge (370088), Namandje N. Bumpus (8452479), Krithika Rajaram (3350864), Hugo Jhun (8153199), Krista A. Matthews (8452476), Anne E. Jedlicka (8452470), Aleah D. Roberts (8452473)   +11 more
core   +1 more source

Sequence and annotation of the apicoplast genome of the human pathogen Babesia microti. [PDF]

PLoS ONE, 2014
The apicomplexan intraerythrocytic parasite Babesia microti is an emerging human pathogen and the primary cause of human babesiosis, a malaria-like illness endemic in the United States.
Aprajita Garg, Anna Stein, William Zhao, Ankit Dwivedi, Roger Frutos, Emmanuel Cornillot, Choukri Ben Mamoun   +6 more
doaj   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Characterization of the apicoplast-localized enzyme TgUroD in Toxoplasma gondii reveals a key role of the apicoplast in heme biosynthesis [PDF]

Journal of Biological Chemistry, 2020
Apicomplexan parasites such as Toxoplasma gondii possess an unusual heme biosynthesis pathway whose enzymes localize to the mitochondrion, cytosol, or apicoplast, a nonphotosynthetic plastid present in most apicomplexans. To characterize the involvement of the apicoplast in the T.
Edwin T. Tjhin, Jenni A. Hayward, Geoffrey I. McFadden, Giel G. van Dooren   +3 more
openaire   +3 more sources