Results 81 to 90 of about 14,891 (174)

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

eLife
The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown.
Hui Dong, Jiong Yang, Kai He, Wen-Bin Zheng, De-Hua Lai, Jing Liu, Hui-Yong Ding, Rui-Bin Wu, Kevin M Brown, Geoff Hide, Zhao-Rong Lun, Xing-Quan Zhu, Shaojun Long   +12 more
doaj   +1 more source

A pyruvate transporter in the apicoplast of apicomplexan parasites

Proceedings of the National Academy of Sciences
Pyruvate lies at a pivotal node of carbon metabolism in eukaryotes. It is involved in diverse metabolic pathways in multiple organelles, and its interorganelle shuttling is crucial for cell fitness. Many apicomplexan parasites harbor a unique organelle called the apicoplast that houses metabolic pathways like fatty acid and ...
Pu Chen, Yukun Chen, Ningbo Xia, Bolin Fan, Zhipeng Niu, Zhengming He, Xu Wang, Jing Yuan, Nishith Gupta, Bang Shen   +9 more
openaire   +2 more sources

The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum

mBio
Dynamins, or dynamin-related proteins (DRPs), are large mechano-sensitive GTPases that mediate membrane dynamics or organellar fission/fusion events. Plasmodium falciparum encodes three dynamin-like proteins whose functions are poorly understood.
Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke   +5 more
doaj   +1 more source

Pyrophosphate homeostasis in multiple subcellular compartments is essential in <i>Plasmodium falciparum</i>. [PDF]

mBio
Nwankwo I, Ke H.
europepmc   +1 more source

Genetic analysis of pyrimidine biosynthetic enzymes in Plasmodium falciparum. [PDF]

PLoS Pathog
Rajaram K, Sievert ML, Elahi R, Blauwkamp J, Dillard LB, Absalon S, Prigge ST.   +6 more
europepmc   +1 more source

Inhibitors of the FASII Metabolic Pathway in <i>Toxoplasma gondii</i>: Advances and Therapeutic Perspectives. [PDF]

Microorganisms
Castillo-Villanueva CJ, Anacleto-Santos J, López-Pérez TJ, Casarrubias-Tabarez B, Fortoul TI, Rojas-Lemus M, López-Valdez N, Vega-Ávila E, Calzada F, López-Camacho PY, Rivera-Fernández N.   +10 more
europepmc   +1 more source

Transporters, an important but poorly studied area of Toxoplasma gondii. [PDF]

Parasit Vectors
Wang L, Jing Y, Yang J, Yang X, Qian J, Fang R, Jian F, Zhang L, Li S.   +8 more
europepmc   +1 more source

Near-complete gapless assembly of <i>Babesia caballi</i> NVSL reference. [PDF]

Microbiol Resour Announc
Grimsley M, Hicks J, Camp P, Murphy G, Sigafoose T.   +4 more
europepmc   +1 more source

The segregation of organelles and organellar genomes across eukaryotic biology. [PDF]

Biochem Soc Trans
Jetishi C, Gerber M, Ochsenreiter T.
europepmc   +1 more source

Is heme metabolism a promising drug target in Toxoplasma gondii? [PDF]

PLoS Pathog
Dou Z.
europepmc   +1 more source