Results 131 to 140 of about 39,255 (266)

Antiadipogenic Effect of Dietary Apigenin through Activation of AMPK in 3T3-L1 Cells

, 2016
Adipocyte differentiation (adipogenesis) is a complex process including the coordinated changes in hormone sensitivity and gene expression in response to various stimuli. Natural compounds are known to be involved in the regulation of this process.
Mafuyu Ono (2132872), Ko Fujimori (308511)   +1 more
core   +1 more source

Phytochemical Profiling and Safety Assessment of Maerua crassifolia Forssk. Aerial Parts Infusion With Pharmacological Validation of Its Analgesic and Anti‐Inflammatory Activities

ChemistryOpen, Volume 15, Issue 11, November 2026.
Rich in phenolic compounds, Maerua crassifolia Forssk. aerial parts infusion combines strong antioxidant capacity with a favorable acute safety profile. It produces dose‐dependent analgesic and anti‐inflammatory effects in vivo, approaching reference‐drug activity.
Leila Benazzi, Saida Ouafi, Redouane Semaoui, Faiza Baali, Jordi Eras, Ramon Canela‐Garayoa, Nadjette Djemouai   +6 more
wiley   +1 more source

Apigenin and its dimeric derivatives in lung cancer therapy: a review of their biological activities and molecular mechanisms

Phytomedicine Plus
Background and objectives: Late diagnosis, metastasis and drug resistance drive the high mortality rate of lung cancer worldwide. Apigenin is a natural flavonoid with low toxicity and multi‑target anticancer properties, naturally present in fruits and ...
Mohammad-Sadegh Lotfi, Majid Jafari-Sabet   +1 more
doaj   +1 more source

Sources, Transmission, and Control of Salmonella in Vertically Integrated Broiler Chicken Production: Farm, Hatchery, and Processing Plant

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Salmonella remains one of the most important foodborne pathogens associated with poultry products, despite substantial progress in processing hygiene and antimicrobial interventions. This review critically examines the sources, transmission routes, and control strategies for Salmonella in vertically integrated broiler production systems ...
Deepak Subedi, Bharath Mallavarapu, Pranita Patil, Abhisek Niraula, Milan Kandel, Sanjay Kumar, Amit Kumar Singh   +6 more
wiley   +1 more source

Biotransformation of Chrysin and Apigenin by Cunninghamella elegans

Chemical and Pharmaceutical Bulletin, 2005
Biotransformation of chrysin by Cunninghamella elegans NRRL 1392 produced apigenin, apigenin 7-sulfate, apigenin 7,4'-disulfate, and a new metabolite identified as chrysin 7-sulfate. On the other hand, fermentation of apigenin, using the same microorganism, yielded apigenin 7-sulfate and apigenin 7,4'-disulfate.
openaire   +3 more sources

A Cilia–Centered Nicotinamide Adenine Dinucleotide (NAD+) Signaling Network Regulates Hypothalamic Lysosomal Homeostasis and Metabolic Aging

Aging Cell, Volume 25, Issue 11, November 2026.
Aging‐associated NAD+ depletion in hypothalamic neurons shortens primary cilia and disrupts CHMP4B trafficking to lysosomes during lysosomal stress, leading to impaired TRPML1–mediated Ca2+ signaling and lysosomal stress responses. Calorie restriction restores hypothalamic NAD+ levels, ciliary structure, and lysosomal homeostasis, thereby improving ...
Se Eun Park, Eun Roh, Jae Woo Park, Seong Jun Kim, So Yeon Jeong, Chae Beom Park, Hyo Sun Lim, Ji Soo Kim, Mun Gyeom Kim, Myeong Ju Kim, Young In Cho, Wontae Jeong, Gil Myoung Kang, Sang‐Yeob Kim, Se Hee Min, Min‐Seon Kim   +15 more
wiley   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, Volume 38, Issue 59, 22 October 2026.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, Volume 13, Issue 59, 23 October 2026.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges. [PDF]

Phytother Res
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Islam MR, Rauf A, Shourav FM, Ogaly HA, Aljohani ASM, Al Abdulmonem W, Badalova K, Iriti M.   +7 more
europepmc   +2 more sources

A Systematic Review of Antidiabetic Mechanisms of Passiflora edulis: Beyond Glycemic Control

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Passiflora edulis demonstrates multitarget antidiabetic effects in preclinical models, particularly through peel‐derived preparations rich in pectin and flavonoids. The evidence indicates improvements in glycemic control, lipid metabolism, oxidative stress, and inflammation, involving pathways related to glucose absorption, insulin signaling, AMPK ...
Luiz Ricardo Teixeira de Farias, Mariáurea Matias Sarandy, Reggiani Vilela Gonçalves, Emanuella de Aragão Tavares, Silvana Maria Zucolotto   +4 more
wiley   +1 more source