Results 81 to 90 of about 260,718 (281)
Honey bees are crucial pollinators that play a vital role in maintaining ecological balance. The colonies of managed honey bees in China increased rapidly in the past 20 years.
Xinying Qu +10 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Cross-linking BioThings APIs through JSON-LD to facilitate knowledge exploration
Background Application Programming Interfaces (APIs) are now widely used to distribute biological data. And many popular biological APIs developed by many different research teams have adopted Javascript Object Notation (JSON) as their primary data ...
Jiwen Xin +6 more
doaj +1 more source
Cognitive Application Program Interface (API) is an API of emerging artificial intelligence (AI)-based cloud services, which extracts various contextual information from non-numerical multimedia data including image and audio.
Sinan Chen +2 more
doaj +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
City of Zagreb Spatial Data Infrastructure
Through the establishment of the Coordination Group for the City of Zagreb Spatial Management IT System, the City of Zagreb has become actively involved in the wider global community by setting up the Zagreb Spatial Data Infrastructure (ZSDI) service. In
Darko Šiško +3 more
doaj
Web API Fragility: How Robust is Your Web API Client
Web APIs provide a systematic and extensible approach for application-to-application interaction. A large number of mobile applications makes use of web APIs to integrate services into apps. Each Web API's evolution pace is determined by their respective
Espinha, Tiago +2 more
core
A linked data-driven & service-oriented architecture for sharing educational resources [PDF]
The two fundamental aims of managing educational resources are to enable resources to be reusable and interoperable and to enable Web-scale sharing of resources across learning communities.
Dietze, Stefan +8 more
core
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

