Results 211 to 220 of about 23,200 (255)
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Apelin/APJ signaling in hypoxia-related diseases
Clinica Chimica Acta, 2015The regulatory peptide apelin is the endogenous ligand for the orphan G protein-coupled receptor APJ. Apelin and APJ exist in a variety of tissues, with special status in the heart, lung and tumors. Consequently, the apelin/APJ system exerts a broad range of activities that affect multiple organ systems.
Lu, He +3 more
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Discovery of a Competitive Apelin Receptor (APJ) Antagonist
ChemMedChem, 2011AbstractThe apelin receptor (APJ) is a class A G‐protein‐coupled receptor (GPCR) and is a putative target for the treatment of cardiovascular and metabolic diseases. Apelin‐13 (NH2‐QRPRLSHKGPMPF‐COOH) is a vasoactive peptide and one of the most potent endogenous inotropic agents identified to date.
N J Maximilian, Macaluso +4 more
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Apelin/APJ system: an emerging therapeutic target for respiratory diseases
Cellular and Molecular Life Sciences, 2020Jia-long Yan +3 more
semanticscholar +1 more source
Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.
Biochemical and Biophysical Research Communications - BBRC, 1998K. Tatemoto +12 more
semanticscholar +1 more source
Age-dependent decline in remyelination capacity is mediated by apelin–APJ signaling
Nature Aging, 2021Masumi Ito +13 more
semanticscholar +1 more source
Apelin/APJ system: A novel therapeutic target for locomotor system diseases.
European Journal of Pharmacology, 2021Jingshun Luo +3 more
semanticscholar +1 more source
Biochimica Et Biophysica Acta Gene Regulatory Mechanisms, 2000
Anne-Marie O'Carroll, Stephen Lolait
exaly
Anne-Marie O'Carroll, Stephen Lolait
exaly