Results 21 to 30 of about 114,772,772 (250)

Determinants of human apolipoprotein [a] secretion from mouse hepatocyte cultures

Journal of Lipid Research, 2001
Efforts to develop an in vitro model system to analyze apolipoprotein [a] (apo[a]) gene transcription, mRNA translation, and protein secretion have been complicated by the limited tissue and species distribution of apo[a] and the presence of regulatory ...
Jin Wang, Jennifer Boedeker, Helen H. Hobbs, Ann L. White   +3 more
doaj   +1 more source

A Study of Serum Apolipoprotein A1, Apolipoprotein B and Lipid Profile in Stroke [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Role of Serum Lipids, Lipoproteins and Lipoprotein related variables in the prediction of Stroke is less clear. Abnormalities in plasma Lipoproteins are the most firmly established and best understood risk factors for Atherosclerosis and ...
Shilpasree AS, Savitri Sahukar, Jayaprakash Murthy, Kiran Kumar   +3 more
doaj   +1 more source

Apo A1/Apo B ratio and acute coronary syndrome among peritoneal dialysis patients

Renal Failure, 2021
Background Acute coronary syndrome (ACS) is prevalent in continuous ambulatory peritoneal dialysis (CAPD) patients. However, the association between the apoprotein profile and ACS is not well known.
Tianlei Chen, Min Yang
doaj   +1 more source

Lipoprotein(a) and its Clinical Importance

Medical Laboratory Journal, 2020
Reports have shown that lipoprotein (Lp)(a) can serve as an indicator of atherosclerosis and cardiovascular diseases. Several cardiovascular disease risk factors including age, ethnicity and type 2 diabetes mellitus have been linked to Lp(a) metabolism ...
farnaz zahedi avval, malihe Moammeri Salahshooh, Fatemeh ‎ sadabadi   +2 more
doaj  

Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol‐Lowering Therapy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Elevated lipoprotein(a) (Lp(a)), a low‐density lipoprotein‐like particle bound to the polymorphic apolipoprotein(a) (apo(a)), may be causal for cardiovascular disease. However, the metabolism of Lp(a) in humans is poorly understood.
Dick C. Chan, Gerald F. Watts, Blai Coll, Scott M. Wasserman, Santica M. Marcovina, P. Hugh R. Barrett   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Novel Mutation in the Apob Gene (Apo B-15.56): A Case Report [PDF]

, 2010
Familial hypobetalipoproteinemia (FHBL) is a rare co-dominant genetic disorder characterized by decrease of plasma low density lipoprotein-cholesterol (LDL-c) or apolipoprotein B (Apo-B) equal to or less than the 5th percentile for the population.
Gaddi A, Tarugi P., Cicero A, Bove M., Bove M, Tarugi P, Carnevali L, Cicero A. F. G., Carnevali L., Gaddi A. V.   +9 more
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Lipoprotein(a) as a risk factor in young patients with Myocardial Infarction: Pathophysiology, clinical implications, and therapeutic perspectives [PDF]

Basic and Clinical Biochemistry and Nutrition
Elevated lipoprotein(a) [Lp(a)] is increasingly recognized as a genetically determined, independent risk factor for premature myocardial infarction (MI).
Alireza Farokhian, Alireza Yavar, Majid Majoochi   +2 more
doaj   +1 more source

Characteristics of lipid metabolism disorders in patients with coronavirus infection-COVID-19 with chronic hepatitis C

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
The aim of the study was to assess individual indicators of lipid metabolism in patients with novel coronavirus infection with chronic hepatitis C (CHC) depending on the severity of COVID-19 and liver fibrosis stage.Object and methods.
E. I. Temnik, D. Y. Konstantinov, L. L. Popova   +2 more
doaj   +1 more source