Results 31 to 40 of about 114,772,772 (250)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Apo[a] size and PNR explain African American-Caucasian differences in allele-specific apo[a] levels for small but not large apo[a]

Journal of Lipid Research, 2006
Apolipoprotein [a] (apo[a]) gene size is a major predictor of lipoprotein [a] level. To determine genetic predictors of allele-specific apo[a] levels beyond gene size, we evaluated the upstream C/T and pentanucleotide repeat (PNR) polymorphisms.
Jill Rubin, Han Jo Kim, Thomas A. Pearson, Steve Holleran, Rajasekhar Ramakrishnan, Lars Berglund   +5 more
doaj   +1 more source

A decreased level of high‐density lipoprotein is a possible risk factor for type 2 diabetes mellitus: A review

Health Science Reports, 2023
Introduction Type 2 diabetes mellitus (T2DM) is characterized primarily by dyslipidemia and hyperglycemia due to insulin resistance. High‐density lipoprotein (HDL) play a significant role in preventing the incidence of dyslipidemia and its complications.
Ali Bayat Bodaghi, Erfan Ebadi, Mohammad Javad Gholami, Reza Azizi, Aref Shariati   +4 more
doaj   +1 more source

GVCs and Productivity

, 2022
Introduction GVCs and Productivity: A Conceptual Review GVC Participation for APO Member Countries Impact of GVC Participation on Productivity Conclusion References ...
Kim, Daehong, Lee, Changkeun, Lee, Si Wook   +2 more
core  

Apo-ferritin-Caged Pt Nanoparticles for Selective Hydrogenation of p‑Chloronitrobenzene

, 2023
Reducing halogenated nitrobenzenes to the corresponding halogenated anilines is a critical process in the production of chemical industries. However, commonly used metal catalysts often require high temperatures and pressurized hydrogen during synthesis ...
Chenlin Lu (8756091), Yakui Chen (15181501), Basudev Maity (2274049), Zheng Liu (28397), Takafumi Ueno (541538), Diannan Lu (1312806), Yinhuan Zhou (15181498), Yilin Zheng (5010101)   +7 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Platelet-to-lymphocyte ratio and serum hsCRP levels in third trimester and adverse pregnancy outcomes in women with gestational diabetes mellitus

Scientific Reports, 2023
Gestational diabetes mellitus (GDM) is a major complication of pregnancy. GDM is associated with a higher risk of adverse pregnancy outcomes (APO). The purpose of this study was to assess the association between third-trimester platelet to lymphocyte ...
Jun Tao, Yun Huang, Yan Li, Wen Dai
doaj   +1 more source

Chd1-apo

, 2017
These are the picked particle stacks used to generate the structure of the apo complex (Figure 6). http://www.pdbe.org/emd-3517 .
Böttcher, Bettina, Tom Owen-Hughes (17315), Ramasubramanian Sundaramoorthy (4556428), Sundaramoorthy, Ramasubramanian, Owen-Hughes, Tom, Bettina Böttcher (402558)   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Apolipoprotein gene polymorphisms and plasma levels in healthy Tunisians and patients with coronary artery disease

Lipids in Health and Disease, 2008
Aim To analyze apolipoprotein gene polymorphisms in the Tunisian population and to check the relation of these polymorphisms and homocysteine, lipid and apolipoprotein levels to the coronary artery disease (CAD).
Hamda Khaldoun, Hassine Mohsen, Moral Pedro, Esteban Esther, Bahri Raoudha, Chaabani Hassen   +5 more
doaj   +1 more source