Results 111 to 120 of about 121,312 (312)
, 2004 Apolipoprotein E (APOE), vitamin B12, and folate were examined in relation to free recall among 167 community-based older adults. Cognitive support at encoding and retrieval was also taken into account.
Kivipelto, M, Wahlin, A, Bunce, D
core
GP73 upregulates APOE and interacts with APOE.
, 2014 (A) APOE mRNA levels in stable Huh7.5.1 cells were quantified using qRT-PCR.
Tao Peng (81319) +4 more
core +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent late‐onset neurodegenerative diseases worldwide. Both are influenced in part by genetic factors and are currently incurable. Tobacco and alcohol, the two most common substances used among the general adult population, are potential AD/PD risk factors and are also ...
Linda Wang +3 more
wiley +1 more source
Apolipoprotein E: A Potential Prognostic and Diagnostic Biomarker for Hepatocellular Carcinoma
Journal of Hepatocellular CarcinomaYuxia Li, Ruijiao Lu, Xieyidai Abuduhailili, Yangchun Feng Department of Clinical Laboratory Center, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, 830000, People’s Republic of ChinaCorrespondence: Yangchun Feng, Email paopao1987123 ...
Li Y, Lu R, Abuduhailili X, Feng Y
doaj
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng +4 more
wiley +1 more source
Statükoculuk'tan ''Çok Yönlü Dış Politika'ya'': ''Komşularla Sıfır Sorun'' değerlendirmesi
, 2012 Türk dış politikası cumhuriyetin kurulmasından itibaren genel olarak üç temel politika üzerine kurulmuştur. Bunlar `Statükocu', `Batıcı' ve `Güvenlikçi' yaklaşımlar olmuştur. Cumhuriyetin kuruluş aşamasında hem Türkiye'nin içinde bulunduğu koşullar hem de dünya konjonktürü bu politikaların yürütülmesinde belirleyici olmuştur ...
openaire +1 more source
Animal Models and Experimental Medicine, EarlyView.The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi +6 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde +9 more
wiley +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway
Archives of Medical ScienceIntroduction Osteosarcoma (OS) is a highly malignant bone tumor with limited treatment options. The role of apolipoprotein E (APOE) in OS remains unclear.
Xiangyang Cheng +5 more
doaj +1 more source