Results 111 to 120 of about 176,190 (308)
Chronological Diagnostic Algorithm Predicting Neuropathology in Parkinsonism
Annals of Neurology, EarlyView.Objective Pre‐mortem diagnosis of parkinsonism is often challenging due to atypical presentations, overlapping syndromes, and co‐pathologies. This study aimed to develop a machine learning‐based algorithm predicting neuropathology in parkinsonism using chronological clinical presentations, which has previously been underexplored.
Daisuke Ono +5 more
wiley +1 more source
, 2016 Η εννοιολογική αλλαγή και εξέλιξη των εννοιών ''ήπιες'', ''εναλλακτικές'' και ''ανανεώσιμες'' ''μορφές'' ή ''πηγές'' ενέργειας όπως εντοπίζεται σε τεχνικά συγγράμματα και περιοδικά, συνέδρια του Ινστιτούτου Ηλιακής Τεχνολογίας και εφημερίδες.
openaire +1 more source
Το περιοδικό του Ε.Ι.Ρ. ''Ραδιοπρόγραμμα'' (1939-1955)
, 2021 Η παρούσα διπλωματική εργασία παρακολουθεί τη δημιουργία και την εξέλιξη της του περιοδικού του Εθνικού Ιδρύματος Ραδιοφωνίας Εβδομαδιαίον Πρόγραμμα και στην συνέχεια Ραδιοπρόγραμμα, από την πρώτη κυκλοφορία του το 1939 έως και την αλλαγή της φυσιογνωμίας του το 1955.
openaire +1 more source
Annals of Neurology, EarlyView.Objective This study aimed to compare positron emission tomography (PET) and plasma‐based temporal modeling of amyloid and tau biomarkers in Alzheimer's disease. Methods Longitudinal amyloid PET (n = 1,097, mean age ± SD = 72.5 ± 7.38 year, 51.4% male), 18F‐flortaucipir tau‐PET (n = 230, 74.3 ± 7.18 year, 52.2% female), and Fujirebio Lumipulse plasma p‐
Christopher A. Brown +14 more
wiley +1 more source
Knowledge means 'all', belief means 'most'
, 2012 We introduce a bimodal epistemic logic intended to capture knowledge as truth in all epistemically alternative states and belief as a generalized 'majority' quantifier, interpreted as truth in many (a 'majority' of the) epistemically alternative states.
Askounis, D., Koutras, C.D., Zikos, Y.
openaire +1 more source
Annals of Neurology, EarlyView.Objective Clinically relevant Alzheimer's disease co‐pathology is common in Lewy body disorders. Plasma P‐tau217 is a sensitive biomarker for amyloid and tau pathology in Alzheimer's disease. The objective was to determine if plasma P‐tau217 associates with Alzheimer's disease co‐pathology and cognition in Lewy body disorders. Methods Participants had (
Thomas F. Tropea +20 more
wiley +1 more source
ApoE gene therapy: an overview and update [PDF]
, 2005 Atherosclerosis remains the leading cause of death in industrialized societies. Apolipoprotein E (ApoE) is an attractive candidate to treat hypercholesterolemia and coronary heart disease, as it is a circulating protein with pleiotropic ...
Owen, J.S.
core
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway
Archives of Medical ScienceIntroduction Osteosarcoma (OS) is a highly malignant bone tumor with limited treatment options. The role of apolipoprotein E (APOE) in OS remains unclear.
Xiangyang Cheng +5 more
doaj +1 more source